Production of Herbal-Based Nanoparticles for Medical Textiles

Abstract

The use of materials created through nanotechnology is expected to dramatically increase over the next few years. Nanotechnology can provide high durability for fabrics because nanoparticles have a large surface area to volume ratio and high surface energy, thus presenting better a±nity for fabrics, leading to an increase in durability of the function. In this study herbal plants such as Curcuma longa and Datura metel were selected, and bioactive compounds were extracted and standardized. Nanoparticles of the medicinal plant extracts were prepared by coacervation method using bovine serum albumin, cross-linked with gluteraldehyde and¯nished on 100% pure cotton by pad-dry-cure method. The antimicrobial activities of the nanoparticlestreated cotton fabrics were found to be higher than that of the control fabrics in both AATCC 147 and Hohestein Challenge test.

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“…The desized fabric was used for disc diffusion assay and quantitative bacterial reduction methods respectively. The desized fabric was primarily coated with citric acid to ensure better binding of the prepared formulation using pad-dry-cure method 16 . For 1 gm of the fabric 20 ml of the nanoparticles and about 1.6 gms of citric acid was used as a binder, the fabric was kept immersed in the treatment solution for 20 minutes.…”

“…The fabrics were then tested for the percentage reduction of bacterial growth after every 5 cycles 16 . The difference in the durability properties between the different treatments of fabrics was analyzed by repeated washing.…”

“…Another study had reported that the nanoparticles have the higher laundering durability to the small particle size, uniform coating and controlled release 16,28 . However, the meagre reduction of bacteria during the initial laundering cycles of the fabric treated with the bulk extract could be attributed to the presence of the binding agent (citric acid) in the fabrics.…”

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“…Chitosan as a biomaterial, found to have an acceleratory effect on wound healing/wound dressing process [7]. It has unique properties such as biocompatibility, Biodegradability and antibacterial activity which makes it a suitable polymer for biomedical applications [8]. The antibacterial activity of chitosan can be enhanced by combining inorganic agents such as Zn, Ag, CuO, TiO2 and Fe [9][10][11][12].…”

Herbal nanoparticles: A patent review

“…[1] Nanoparticles (NPs) measure approximately 1 -1000 nm in dimension and exhibit properties different from their macroscale counterparts. [2] The nanonization of phytoceuticals leads to a high surface area to volume ratio, enhancement in solubility and bioavailability, reticuloendothelial system (RES) uptake, an enhanced permeability and retention (EPR) effect, improvement in tissue distribution of macrophages, sustained release, enhanced physicochemical stability, and so on. [3] NPs contain the drug embedded in the matrix or absorbed onto the surface.…”