Production of Fatty Acids and Derivatives Using Cyanobacteria

Sattayawat, Pachara; Yunus, Ian Sofian; Jones, Patrik R.

doi:10.1007/10_2022_213

Cited by 1 publication

(1 citation statement)

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“…Finally, the C-terminal of the thioesterase (TE) domain catalyzes dehydration and decarboxylation reactions to produce the advanced biofuels olefin [ 80 ]. For example, 1-nonadecene [ 81 ] and 1,14-nonadecadiene can be synthesized according to this engineering strategy using curM-encoding enzyme with ORF ols as the agent responsible for expressing olefin synthase [ 82 , 83 ]. Some various short-chain ketones (C5–C7) such as ethyl ketone, methyl ketone can be produced by introducing a hybrid polyketide synthase (PKS) via fusing a PKS subunit of lipomycin synthase LipPks1 and a thioesterase (TE) in Streptomyces hosts [ 84 ].…”

Section: Biosynthetic Pathways Of Advanced Biofuels Via Expanding Car...mentioning

confidence: 99%

Biosynthesis pathways of expanding carbon chains for producing advanced biofuels

Lin

2023

Biotechnol Biofuels

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Because the thermodynamic property is closer to gasoline, advanced biofuels (C ≥ 6) are appealing for replacing non-renewable fossil fuels using biosynthesis method that has presented a promising approach. Synthesizing advanced biofuels (C ≥ 6), in general, requires the expansion of carbon chains from three carbon atoms to more than six carbon atoms. Despite some specific biosynthesis pathways that have been developed in recent years, adequate summary is still lacking on how to obtain an effective metabolic pathway. Review of biosynthesis pathways for expanding carbon chains will be conducive to selecting, optimizing and discovering novel synthetic route to obtain new advanced biofuels. Herein, we first highlighted challenges on expanding carbon chains, followed by presentation of two biosynthesis strategies and review of three different types of biosynthesis pathways of carbon chain expansion for synthesizing advanced biofuels. Finally, we provided an outlook for the introduction of gene-editing technology in the development of new biosynthesis pathways of carbon chain expansion.

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Section: Biosynthetic Pathways Of Advanced Biofuels Via Expanding Car...mentioning

confidence: 99%

Biosynthesis pathways of expanding carbon chains for producing advanced biofuels

Lin

2023

Biotechnol Biofuels

View full text Add to dashboard Cite

show abstract

Production of Fatty Acids and Derivatives Using Cyanobacteria

Cited by 1 publication

References 82 publications

Biosynthesis pathways of expanding carbon chains for producing advanced biofuels

Biosynthesis pathways of expanding carbon chains for producing advanced biofuels

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