Production of Alkaloids with Immobilized Cells of Catharanthus Roseus

Production of Alkaloids in Plant Cell Culture

“…The main area of opportunity with immobilized plant cells, however, undoubtedly rests with the de novo synthesis of chemically complex molecules from simple carbon and nitrogen sources , i.e., the production of serpentine and ajmalicine by immobilized cells of C. roseus (Lambe et al, 1982).…”

Plant Cell Bioreactors: Present Status and Future Trends

“…Gel sntrapment has been the most widely used method for plant cell immobilization [36][37][38][39][40]. Higher concentrations 3f secondary metabolites are obtained with immobilized plant cells as compared to suspension cultures [41]. Gels used for immobilization purposes are usually alginate, agar, carrageenan, and polyacrylamide.…”

Immobilized plant cells

“…Shake flasks used as batch reactors 16), and simple packed bed reactors ~o. 33), have been used most frequently, but Mantell and Smith 19) have used alginate immobilized tobacco cells in an air lift reactor.…”