Production and characterization of monoclonal antibodies to embryo-associated immunosuppressor factor (EASF) produced by human pre-implantation embryo

Bose, Ratna; Nagy, Éva; Fleetham, Judy; Pattinson, H. Anthony; Berczi, István; Yang, J.

doi:10.1016/0165-2478(93)90117-k

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“…Murine monoclonal antibodies (Mabs) were produced against preimplantation EASF (EASF isolated from human in vitro fertilized embryo growth media). These EASF-specific Mabs were able to recognize and neutralize biologically active immunosuppressive components in embryo growth media (27). Recently these Mabs were used to immunohistochemically localize EASF in human placental tissues (28).…”

Section: An Update On the Identity Of Early Pregnancy Factor And Its mentioning

confidence: 99%