Proctitis and Proctosigmoiditis -A Need to Identify the Extent of Disease in Epidemiological Surveys

Venkataraman, Jayanthi; Chuah, Seng-Kee; Probert, Chris; Mayberry, Margaret K; Mayberry, J F

doi:10.1159/000201013

Cited by 9 publications

(3 citation statements)

References 7 publications

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“…15 Lesions are usually confined to rectum but may extend proximally to engage sigmoid colon. 25 We noted that 4.1% of the cases had normal pathological findings. Previous findings also revealed that about 6-10% of the children having LGIB represent normal pathological findings.…”

Section: Discussionmentioning

confidence: 71%

Etiologies and outcome of lower gastrointestinal bleeding in patients presenting to a tertiary care Children’s Hospital

et al. 2021

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Objective: To determine etiology and outcome of children with lower gastrointestinal bleeding (LGIB). Methods: This was a prospective study conducted at the Department of Pediatric Gastroenterology and Hepatology, Children’s Hospital and The Institute of Child’s Heath, Multan, Pakistan, from July 2019 to March 2020. A total of 148 cases presented with bleeding per rectum and underwent colonoscopy, were included. Children of both genders and aged three month to 15 years were included. Detailed history, clinical examination, laboratory studies, colonoscopy and histopathology were done in all cases. Study information like demographics, complaints, general clinical examination, colonoscopy and histopathological findings were recorded. Results: Overall, mean age was noted to be 7.20±1.83 years. Abdominal pain was reported in 41 (27.7%), diarrhea 36 (24.3%), fever 12 (8.1%) and constipation in 4 (2.7%). Pallor was noted among 68 (45.9%), weight loss 39 (26.3%) and tachycardia 31 (20.9%). Colonoscopy revealed juvenile colonic / rectal polyps, infectious colitis and solitary rectal ulcer (SRU) as the most common etiologies found among 58 (39.2%), 20 (13.5%) and 19 (12.8%) cases respectively. Juvenile polyps and non-specific colitis were the commonest histopathological findings seen in 55 (37.2%) and 20 (13.5%) cases respectively. Colonoscopic polypectomy was used to remove all juvenile polyps. Conclusion: LGIB is presentation of various underlying causes. Children with LGIB commonly present with abdominal pain. Juvenile polyps were the most frequent cause of LGIB among children flowed by non-specific colitis. Most of the children having LGIB were diagnosed and treated successfully, few are in remission and very few were found resistant to treatment. doi: https://doi.org/10.12669/pjms.37.2.2676 How to cite this:Talib MA, Aziz MT, Suleman H, Khosa GK, Joya SJ, Hussain I. Etiologies and outcome of lower gastrointestinal bleeding in patients presenting to a tertiary care Children’s Hospital. Pak J Med Sci. 2021;37(2):---------. doi: https://doi.org/10.12669/pjms.37.2.2676 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionmentioning

confidence: 71%

Etiologies and outcome of lower gastrointestinal bleeding in patients presenting to a tertiary care Children’s Hospital

et al. 2021

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“…18 Lesions are restricted to the rectum, but may extend proximally to involve the sigmoid colon. 19 In our study, all children with non-specific proctitis were excluded for helminthic infections and the diagnosis was confirmed histologically in 35 (92%) cases from rectal biopsy. In follow up, rectal bleeding recurred in eight (21%) children, and their sigmoidoscopic examination showed healing in 63% ( n = 5) of cases; however, they had small sessile polyps.…”

Section: Discussionmentioning

confidence: 92%

“…It is often considered a variant of diffuse ulcerative colitis, but the condition differs in its clinical manifestations and prognosis from ulcerative colitis 18 . Lesions are restricted to the rectum, but may extend proximally to involve the sigmoid colon 19 . In our study, all children with non‐specific proctitis were excluded for helminthic infections and the diagnosis was confirmed histologically in 35 (92%) cases from rectal biopsy.…”

Section: Discussionmentioning

confidence: 99%