Sigmoidoscopy in children with chronic lower gastrointestinal bleeding

Mandhan, Parkash

doi:10.1111/j.1440-1754.2004.00403.x

Cited by 30 publications

(42 citation statements)

References 23 publications

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“…In comparison, NH was described with a frequency of 3% in a previous report (27). NH of the GI tract results from hyperproliferation of lymphoid cells as a result of immune stimulation.…”

Section: Discussionmentioning

confidence: 99%

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A survey on rectal bleeding in children, a report from Iran

2018

Turk J Med Sci

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Background/aim: Studies on the epidemiology of rectal bleeding in children are limited in Iran. Our aim was to assess etiologies of rectal bleeding in children in Iran. Materials and methods:We enrolled 730 children with rectal bleeding. All the patients underwent colonoscopy, and 457 were further evaluated with histopathology.Results: According to colonoscopy and histopathology, respectively, inflammatory bowel disease (IBD) (29.4%, 15.8%), nodular hyperplasia (NH) (24.9%, 10%), and juvenile polyposis (JP) (12.6%, 9.9%) were the most common causes of rectal bleeding. Other conditions were solitary rectal ulcer (5.3%), chronic colitis (4.6%), allergic colitis (3.3%), focal colitis (1.3%), and infectious colitis (1.1%). In colonoscopy, there were no significant differences in the distribution of pathologies regarding sex, while the youngest and oldest mean ages were found for patients with NH (4.6 ± 3.9 years, P < 0.0001) and those with normal appearance (8.1 ± 4.4 years, P < 0.0001) respectively. Based on histopathologic reports, the youngest patients were diagnosed with infectious colitis (4.6 ± 2.8 years), while patients with chronic colitis were the oldest (9.2 ± 4.6 years, P = 0.003). Conclusion:JP, NH, and IBD constituted the most common etiologies of rectal bleeding in our patients. It is recommended to perform a complete diagnostic approach to accurately assess rectal bleeding in children.

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“…In comparison, NH was described with a frequency of 3% in a previous report (27). NH of the GI tract results from hyperproliferation of lymphoid cells as a result of immune stimulation.…”

Section: Discussionmentioning

confidence: 99%

“…Of these, 72 cases were confirmed as JP, while 21 patients showed nonjuvenile polyps in histological examination. JP in the colorectal area has been the most common etiology for GI bleeding in children (27). Frequency of JP among children with rectal bleeding is variable.…”

Section: Discussionmentioning

confidence: 99%

A survey on rectal bleeding in children, a report from Iran

2018

Turk J Med Sci

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“…[4,7,19] The characteristic histopathological findings of SRUS that provide differentiation from other diseases are obliteration with increased fibroblastic activity and presence of collagen deposition in the lamina propria, distortion of crypt architecture, lack of epithelial dysplasia, regenerative changes in crypt epithelium, and muscle fibers derived from muscularis mucosa in the surrounding tissue. [1,7,9,12,13,16,17] The diagnosis of SRUS is established by appraising symptoms together with endoscopic appearance and histopathologic findings. Since it is quite rare in children and symptoms are not characteristic, clinicians, endoscopists and pathologists should keep SRUS in mind to prevent delayed diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…The incidence of SRUS was reported by ElKhayat et al and by Mandhan to be 1.5% in children with rectal bleeding and 3.5% within chronic lower GI bleeding, respectively. [1,3] However, the exact incidence is unknown in childhood.…”

mentioning

confidence: 99%

“…[1,2] Although solitary rectal ulcer syndrome (SRUS) causing lower GI bleeding is relatively well documented in adult series, pediatric cases are extremely rare, and only a few case reports have been published. The incidence of SRUS was reported by ElKhayat et al and by Mandhan to be 1.5% in children with rectal bleeding and 3.5% within chronic lower GI bleeding, respectively.…”

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confidence: 99%

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A Rare Cause of Chronic Rectal Bleeding in Children: Solitary Rectal Ulcer (Case Report)

Temız

Tander²,

Temiz³

et al. 2011

Ulus Travma Acil Cerrahi Derg

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Prevalence of Colorectal Polyps in Pediatric Colonoscopy

et al. 2011

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Background The available data regarding the prevalence, types, and clinical determinants of colonic polyps in children is limited. Aims We aimed to estimate the prevalence of colorectal polyps in a large cohort of children. Methods We conducted a cross-sectional study to determine the presence, number, and location of colorectal polyps reported in all children (0–20 years) who underwent colonoscopy at 14 pediatric facilities between January 2000 and December 2007 recorded in Pediatric Endoscopy Database System Clinical Outcomes Research Initiative (PEDS-CORI). We compared procedures with and without polyps with respect to procedure indication, age, sex, and race. We also reviewed a sample of histopathologic reports from one participating center. Results We analyzed 13,115 colonoscopy procedures performed in 11,637 patients. Colorectal polyps were reported in 810 procedures (6.1%; 95% CI: 5.7% to 6.5%) performed in 705 patients, and in 12% of patients with lower GI bleeding. Children with colorectal polyps were significantly younger (8.9y vs. 11.9y; p<0.0001), male (58.3% vs. 49.0%; p<0.001), non-white race (27.5% vs. 21.9%; p<0.001), and had lower GI bleeding (54.4% vs. 26.6%; p<0.001) as compared to children without polyps. In a sample of 122 patients with polyps from a single center, the histological types were solitary juvenile in 91 (70.5%), multiple juvenile in 20 (15.5%), adenoma in 14 (10.9%) and hyperplastic polyps in 4 patients (3.1%). Conclusions Colorectal polyps are detected in 6.1% overall and in 12.0% among those with lower gastrointestinal bleeding during pediatric colonoscopy. Approximately 26% are multiple juvenile or adenoma.

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Sigmoidoscopy in children with chronic lower gastrointestinal bleeding

Abstract: Rigid sigmoidoscopy was useful in diagnosis, treatment and prognostic evaluation of children with chronic and minor lower gastrointestinal bleeding. Final diagnosis was confirmed by histopathology.

Cited by 30 publications

References 23 publications

A survey on rectal bleeding in children, a report from Iran

A survey on rectal bleeding in children, a report from Iran

A Rare Cause of Chronic Rectal Bleeding in Children: Solitary Rectal Ulcer (Case Report)

Prevalence of Colorectal Polyps in Pediatric Colonoscopy

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