Pro-angiogenic actions of Salvianolic acids on in vitro cultured endothelial progenitor cells and chick embryo chorioallantoic membrane model

Mechanism of angiogenesis promotion with Shexiang Baoxin Pills by regulating function and signaling pathway of endothelial cells through macrophages

“…Our research on SBP will be beneficial for investigating the molecular mechanism of other traditional Chinese medicines with angiogenic activities such as Panax ginseng [33], Salvia miltiorrhiza [34] and Radix bupleur [35]. In another study we conducted, we discovered that salvianolate, an effective component in Salvia miltiorrhiza, has antiischemic cerebral infarction effects by promoting angiogenesis through macrophages.…”

Endothelial Progenitor Cell Dysfunction in Cardiovascular Diseases: Role of Reactive Oxygen Species and Inflammation

“…In addition to clinical drugs, several antioxidative agents with anti-inflammatory properties, such as puerarin [104, 105], resveratrol/red wine [106–113], Ginkgo biloba [114], berberine [115], salvianolic acids [116], and ginsenoside [117], also have been found to enhance EPC bioactivity (Figure 3). In theory, decrease in oxidative stress would induce mobilisation of EPCs and improve their functionality [64].…”

Enumeration and functional investigation of endothelial progenitor cells in neovascularization of diabetic foot ulcer rats with a Chinese 2‐herb formula

“…Li et al. presented similar results of EPCs in the vasculogenesis assay with the use of Danshen for patients with coronary artery disease . Besides, Gao et al.…”

“…35 Li et al presented similar results of EPCs in the vasculogenesis assay with the use of Danshen for patients with coronary artery disease. 36 Besides, Gao et al showed that Xuefu Zhuyu Decoction induced EPCs tube formation in treating ischemic diseases. 37 Until now, it still remains unclear about the influence of TCM treatment in EPCs biology in relation to diabetic wound healing.…”