Abstract:terms of observable characteristics such as age, gender, and comorbidities (pϽ0.001). Samples were balanced with nearest neighbor matching. Then segmented time-series models were applied. There was a significant association between the onset of intervention and the level of utilization of these drugs. CONCLUSIONS: To isolate the effects of guidelines, we need to control for three different factors: 1) baseline differences between the two groups; 2) stepwise differences at the intervention point; and 3) trend d… Show more
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