Principal components analysis

Afifi, Abdelmonem A.; May, Susanne; Donatello, Robin A.; Clark, Virginia A.

doi:10.1007/978-1-4899-3342-3_14

Cited by 5 publications

(7 citation statements)

References 7 publications

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“…H. pylori effect within LTBI). For multiplex-cytokine analysis, Principal Components Analysis [27] was performed with the correlation matrix composed of six variables found to discriminate by Wilcoxon's test between 40 latently infected and 25 controls ( Tables S1 and S2 ), and components having Eigenvalue >1 were selected to compute summary component scores for each subject using eigenvector coefficients.…”

Section: Methodsmentioning

confidence: 99%

Infection with Helicobacter pylori Is Associated with Protection against Tuberculosis

et al. 2010

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Background Helicobacter pylori, a lifelong and typically asymptomatic infection of the stomach, profoundly alters gastric immune responses, and may benefit the host in protection against other pathogens. We explored the hypothesis that H. pylori contributes to the control of infection with Mycobacterium tuberculosis.Methodology/Principal FindingsWe first examined M. tuberculosis-specific IFN-γ and H. pylori antibody responses in 339 healthy Northern Californians undergoing routine tuberculin skin testing. Of 97 subjects (29%) meeting criteria for latent tuberculosis (TB) infection (LTBI), 45 (46%) were H. pylori seropositive. Subjects with LTBI who were H. pylori-seropositive had 1.5-fold higher TB antigen-induced IFN-γ responses (p = 0.04, ANOVA), and a more Th-1 like cytokine profile in peripheral blood mononuclear cells, compared to those who were H. pylori seronegative. To explore an association between H. pylori infection and clinical outcome of TB exposure, we evaluated H. pylori seroprevalence in baseline samples from two high risk TB case-contact cohorts, and from cynomolgus macaques experimentally challenged with M. tuberculosis. Compared to 513 household contacts who did not progress to active disease during a median 24 months follow-up, 120 prevalent TB cases were significantly less likely to be H. pylori infected (AOR: 0.55, 95% CI 0.0.36–0.83, p = 0.005), though seroprevalence was not significantly different from non-progressors in 37 incident TB cases (AOR: 1.35 [95% CI 0.63–2.9] p = 0.44). Cynomolgus macaques with natural H. pylori infection were significantly less likely to progress to TB 6 to 8 months after M. tuberculosis challenge (RR: 0.31 [95% CI 0.12–0.80], p = 0.04).Conclusions/Significance H. pylori infection may induce bystander effects that modify the risk of active TB in humans and non-human primates. That immunity to TB may be enhanced by exposure to other microbial agents may have important implications for vaccine development and disease control.

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Section: Methodsmentioning

confidence: 99%

Infection with Helicobacter pylori Is Associated with Protection against Tuberculosis

et al. 2010

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“…We used the Kaiser-Meyer-Olkin measure to test the suitability of the items for factor analysis. The decision on how many factors to retain was made using Kaiser's rule of retaining only factors with eigenvalues of 1 or higher and examining the "elbow" of the scree plot (plot of eigenvalues) (Afifi, Clark, & May, 2004;DeVellis, 2016;Hinkin et al, 1997). Oblique rotation, which allows for correlation between the rotated factors, was used because the person-centered care domains are theoretically related (Afifi et al, 2004;Hinkin et al, 1997).…”

Section: Psychometric Analysesmentioning

confidence: 99%

Adaptation of the Person-Centered Maternity Care Scale in the United States: Prioritizing the Experiences of Black Women and Birthing People

Afulani¹,

Altman²,

Castillo³

et al. 2022

Women's Health Issues

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“…Dietary patterns give more insights into real-life conditions and may have a greater effect on health outcomes than amounts of individual foods or nutrients (18) . Principal component analysis (PCA) is an established multivariate technique to reduce food consumption data to a smaller number of underlying factors or dietary patterns (19,20) . These patterns are uncorrelated with each other and explain variations in food intake across a population.…”

mentioning

confidence: 99%

Dietary patterns among British adults: compatibility with dietary guidelines for salt/sodium, fat, saturated fat and sugars

Gibson¹,

Ashwell

2011

Public Health Nutr.

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Principal components analysis

Cited by 5 publications

References 7 publications

Infection with Helicobacter pylori Is Associated with Protection against Tuberculosis

Infection with Helicobacter pylori Is Associated with Protection against Tuberculosis

Adaptation of the Person-Centered Maternity Care Scale in the United States: Prioritizing the Experiences of Black Women and Birthing People

Dietary patterns among British adults: compatibility with dietary guidelines for salt/sodium, fat, saturated fat and sugars

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