Primary Ureteral Hemangiosarcoma in a dog

Abstract

Background Primary ureteral neoplasia in dogs is extremely rare. To the best of the authors’ knowledge, this is the second documented case of a primary ureteral hemangiosarcoma. This case report describes the clinical and pathological findings of a primary distal ureteral hemangiosarcoma. Case presentation A 12-year-old spayed female goldendoodle was presented with a history of polyuria and weight loss. Abdominal radiographs revealed a large cranial abdominal mass. Abdominal ultrasound and computed tomography (CT) identified a left sided distal ureteral mass with secondary hydroureter and a left lateral hepatic mass with no evidence of connection or diffuse metastasis. A left ureteronephrectomy, partial cystectomy, and left lateral liver lobectomy were performed. Histopathology was consistent with primary ureteral hemangiosarcoma and a hepatocellular carcinoma. Adjunctive therapy including chemotherapy was discussed but declined. Conclusion Due to its rarity, the authors of this case presentation believe that ureteral hemangiosarcoma should be included as a differential diagnosis when evaluating a ureteral mass. With the unknown, and suspected poor prognosis, routine monitoring with adjunctive therapy should be considered.

Ureteral rhabdomyosarcoma in a dobermann

“…Reported treatment options for primary tumours of the ureter in dogs include ureteroneocystostomy or ureteronephrectomy. 13 There is lack of evidence in the veterinary literature supporting the use of chemotherapy in malignant primary ureteral tumours. In our described case, the low-grade nature of the tumour and complete excision meant that adjuvant chemotherapy or radiotherapy were not considered to be in the patient's best interest.…”

“…More frequently, tumours originate in the bladder or urethra and extend to the ureterovesical junction, where they can infiltrate into the ureteral lumen or wall. 23 Reported cases of primary ureteral tumours include a poorly differentiated high-grade sarcoma (1), 2 soft tissue sarcoma (1), 3 spindle cell sarcoma (1), 4 giant cell sarcoma (1), 5 leiomyosarcoma (2), 6,7 leiomyoma (2), 8,9 transitional cell carcinoma (3), [10][11][12] haemangiosarcoma (2), 13,14 fibroepithelial polyps (8), [15][16][17] fibropapilloma (1) 18 and a mast cell tumour (1). 19 We presented a case of rhabdomyosarcoma originating in the distal part of the right ureter of a dog.…”

“…1 Primary ureteral tumours are very uncommon in dogs, and only 23 cases have been reported in the veterinary literature. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Ureteral sarcomas have been described previously, but a literature search did not identify any reported ureteral rhabdomyosarcomas in dogs.…”

Neoplasias del sistema urinario en perros y gatos

“…Dentre os neoplasmas primários relatados cita-se o papiloma de célula de transição, carcinoma de célula de transição, liomioma, liomiossarcoma, fibropapiloma e o mastocitoma (Carvalho et al, 2016). Polit et al (2020) relataram o segundo caso de hemangiossarcoma ureteral primário descrito em cães. Enquanto que Steffey et al (2004) relataram o primeiro caso em canino de mastocitoma ureteral.…”

“…Em um paciente canino relado por Hanika & Rebar (1980), com diagnóstico de carcinoma de células transicionais ureteral invasivo, o tratamento instituído foi nefroureterectomia unilateral e após dez meses não houve qualquer sinal de recorrência; porém, admite-se que a recidiva pode ocorrer. Já no paciente canino diagnosticado com hemangiossarcoma ureteral primário, foi realizado uma nefroureterectomia unilateral e cistectomia parcial devido invasão na vesícula urinária (Polit et al, 2020). Enquanto que no canino com diagnóstico mastocitoma, o tratamento instituído foi uma ureteroneocistostomia, mas após cinco meses ocorreu o óbito do paciente devido a outros neoplasmas não relacionados com o tumor em questão e também sendo confirmado na necropsia que não houve recidiva do tumor ureteral (Steffey et al, 2004).…”