Primary Trabeculectomy in Young Adults

Costa, Vital Paulino; Katz, L. Jay; Spaeth, George L.; Smith, Maura; Gandham, Sai B.

doi:10.1016/s0161-6420(93)31536-8

Cited by 44 publications

(20 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They demonstrated that the success rate for primary glaucomas (74%) was significantly higher than for secondary (48%) or developmental (35%) glaucomas. Costa et al [12] also showed a similar success rate Yalvac/Nurözler/Kahraman/Kasim/Duman (83%) of primary trabeculectomy in patients 15-40 years of age with uncomplicated (juvenile, pigmentary, low-tension) glaucomas. Among the eyes with complicated glaucomas (inflammatory, ICE syndrome, traumatic, Axenfeld-Rieger syndrome) the success rate was lower and they concluded that the use of antimetabolite therapy should be restricted to young adults with refractory glaucomas or with previous intraocular or conjunctival surgery.…”

Section: Discussionmentioning

confidence: 65%

The Results of Trabeculectomy with and without Mitomycin C in Young Patients

Yalvaç

Nurözler²,

Kahraman³

et al. 1998

Ophthalmologica

View full text Add to dashboard Cite

The results of primary trabeculectomy with and without mitomycin C (MMC) were evaluated in young glaucoma patients. The patients, 15–40 years of age, were divided into two main groups and two subgroups. In group IA, primary Cairns type trabeculectomy was performed in 24 eyes of 24 patients with juvenile glaucoma; in group IB, trabeculectomy + MMC 0.4 mg/ml in 3 min was done in 20 eyes of 20 patients with juvenile glaucoma; in group IIA, primary trabeculectomy was performed in 20 eyes of 20 patients with developmental glaucoma, and in group IIB, trabeculectomy + MMC 0.4 mg/ml in 3 min was performed in 16 eyes of 16 patients with developmental glaucoma. The success rate of the surgery was 75% in group IA, 90% in group IB, 50% in group IIA, and 75% in group IIB. There was no statistically significant difference among the groups in terms of success rates of trabeculectomies (p > 0.05).

show abstract

Section: Discussionmentioning

confidence: 65%

The Results of Trabeculectomy with and without Mitomycin C in Young Patients

Yalvaç

Nurözler²,

Kahraman³

et al. 1998

Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…Krupin et al [24] reported that younger age was associated with a higher incidence of long-term hypotony in primary trabeculectomy in phakic patients. Recently, Costa et al [8] reported a higher success rate of trabculectomy without use of an antimetabolite in younger patients with uncomplicated glaucoma. Although we have no good explanation for the finding with respect to patients' age, this age effect may be considered in adjusting the filtration intraoperatively or postoperatively.…”

Section: Discussionmentioning

confidence: 99%

Conditions for balance between lower normal pressure control and hypotony in mitomycin trabeculectomy

Hara

Araie

Shirato

et al. 1998

Graefe's Archive for Clinical and Experimental Ophthalmology

View full text Add to dashboard Cite

show abstract

“…In a number of studies, it has been concluded that filtering surgery is less successful for younger glaucoma patients than is the case for older glaucoma patients [2, 3, 4]. Failure of glaucoma surgery amongst young patients may be related to a thicker Tenon’s capsule and a more active scarring response as compared with older glaucoma patients.…”

Section: Introductionmentioning

confidence: 99%

Trabeculectomy with Mitomycin C versus Trabeculectomy Alone for Juvenile Primary Open-Angle Glaucoma

et al. 2003

View full text Add to dashboard Cite

Purpose: We compare the intermediate-term outcome of initial trabeculectomy with adjunctive mitomycin C use versus initial trabeculectomy alone for juvenile primary open-angle glaucoma. Methods: This retrospective consecutive analysis included 44 eyes from 36 patients with juvenile primary-open angle glaucoma, all of whom underwent either initial trabeculectomy with adjunctive mitomycin C use (15 eyes) or initial trabeculectomy alone without mitomycin C use (29 eyes). We compared the success rate and complications between the two groups in a three-year follow-up period following surgery. Results: Three years subsequent to surgery, the cumulative success probability was 73% for the mitomycin C group and 68% for the control group, there being no real difference between the two groups (p = 0.89). A greater incidence of hypotony maculopathy was found amongst the mitomycin C group than was the case for the control group (20 versus 0%, respectively, p = 0.034). A lower intraocular pressure amongst the mitomycin C group was noted as compared with the control group (10.8 ± 3.0 versus 13.3 ± 3.8 mm Hg, respectively, p = 0.017) amongst the successfully treated patients. Conclusions: Despite the lower intraocular pressure level for the successfully treated patients from the trabeculectomy with mitomycin C group, and a greater incidence of resultant hypotony maculopathy for this group as compared with the trabeculectomy alone group, there appeared to be no significant difference in the cumulative success probability for this group as compared with the trabeculectomy alone group. Therefore, we caution against the use of an initial trabeculectomy with mitomycin C for juvenile primary open-angle glaucoma.

show abstract

Primary Trabeculectomy in Young Adults

Cited by 44 publications

References 28 publications

The Results of Trabeculectomy with and without Mitomycin C in Young Patients

The Results of Trabeculectomy with and without Mitomycin C in Young Patients

Conditions for balance between lower normal pressure control and hypotony in mitomycin trabeculectomy

Trabeculectomy with Mitomycin C versus Trabeculectomy Alone for Juvenile Primary Open-Angle Glaucoma

Contact Info

Product

Resources

About