Primary thoracic muscle tuberculosis: two case reports

Grigorakos, Leonidas; Sgountzos, Vassilis; Lazarescu, Daria; Simopoulou, Sophia; Gkouni, Magda; Μάρκου, Νικόλαος; Tamvakis, Vassilis

doi:10.1186/s13256-016-0996-2

Cited by 8 publications

(5 citation statements)

References 6 publications

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“…The most common histological features of MT included granulomatous inflammation, caseous necrosis, and epithelioid granulomata. The TB test could be partially negative, which does not rule out TB infection ( 26 ). Among the available modalities, serological tests and PPD skin tests were not recommended in the diagnosis of MT or the initiation of antituberculosis treatment.…”

Section: Discussionmentioning

confidence: 99%

Case report: Muscular tuberculosis with lower-extremity muscular masses as the initial presentation: Clinicopathological analysis of two cases and review of the literature

et al. 2023

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BackgroundTuberculosis (TB) is a threat to public health that mostly affects people in developing countries. TB presenting as a soft tissue mass is rare and is usually seen in patients with muscular tuberculosis (MT).Case presentationIn this study, we present the clinical, radiographic, and pathological features of two cases and retrospective evaluations of an additional 28 patients who were diagnosed with MT. More patients were men (60.9%) than women (39.1%), with a male-to-female ratio of 1.6:1. The average age among male and female patients was 38.9 and 30.1 years, respectively. MT usually presents with painful or painless muscular nodules on the lower limbs. Imaging findings, including ultrasound, CT, and MRI, can be used to identify lesions and sites for biopsy. The most typical histopathological feature of MT is granulomatous inflammation with caseous necrosis and epithelioid granulomata. Acid-fast bacilli stain and polymerase chain reaction (PCR) assays are helpful in identifying tubercle bacillus.ConclusionWe describe two MT cases with lower-extremity muscular masses as the initial presentation. The results suggest that muscle biopsy and pathological analysis remain necessary for diagnosis. Most of the patients could be cured with standard antituberculosis therapy.

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Section: Discussionmentioning

confidence: 99%

Case report: Muscular tuberculosis with lower-extremity muscular masses as the initial presentation: Clinicopathological analysis of two cases and review of the literature

et al. 2023

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“…Pectoralis major tuberculosis is exceedingly uncommon, with few case reports available [ 5 ]. Although the precise cause of muscle tissue's resistance to tubercle bacillus is unknown, the presence of lactic acid, scarcity of reticulo-epithelial tissue, and low oxygen levels in muscle tissue have been suggested [ 6 - 7 ].…”

Section: Introductionmentioning

confidence: 99%

Musculoskeletal Tuberculosis of the Pectoralis With Bilateral Pleural Base Nodular Lesions: A Rare Report of Its Type in an Immunocompetent Female

Yadav

2024

Cureus

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Musculoskeletal tuberculosis is a rare infection caused by Mycobacterium tuberculosis. This type of extrapulmonary tuberculosis is mainly attributed to hematogenous infection or direct inoculation and is usually seen in immunocompromised individuals. Here, a case of musculoskeletal tuberculosis of the right pectoralis with bilateral pleural base nodular lesions in an immunocompetent female is presented. A challenging diagnosis was achieved through a detailed clinical examination, aspiration of the pus, and radiometric investigations. Management was done through antituberculous chemotherapy per the national guidelines. Further, a detailed literature review revealed that tuberculosis of the pectoralis with bilateral pleural base nodular lesions is never reported in an immunocompetent female.

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“…Muscle tissue is resistant to tubercle bacillus, the reason for this resistance is unclear, but it has been attributed to the low amount of oxygen in muscle tissue and the presence of lactic acid 6,7 .…”

Section: Introductionmentioning

confidence: 99%

Chest wall soft-tissue tuberculosis: A case report

Álvarez-Moran¹,

Ávila-Sánchez

Fernández-Lara³

2020

HGMX

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Chest wall tuberculosis (TB) is a rare condition, making up 1-5% of all musculoskeletal TB cases. We report a case of a 39-year-old woman with a palpable mass on the right hemithorax with a 3-month evolution. The computed tomography scan showed a mass of 4 cm above the pectoralis major muscle. Complete removal of the tumor was performed, which showed caseous material with positive polymerase chain reaction for Mycobacterium tuberculosis. The patient has not presented any symptoms 6 months after a quadruple-based therapy. We emphasize the fact of suspecting this pathology, when soft-tissue masses are found on the chest wall, due to its rare localization.

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Primary thoracic muscle tuberculosis: two case reports

Cited by 8 publications

References 6 publications

Case report: Muscular tuberculosis with lower-extremity muscular masses as the initial presentation: Clinicopathological analysis of two cases and review of the literature

Case report: Muscular tuberculosis with lower-extremity muscular masses as the initial presentation: Clinicopathological analysis of two cases and review of the literature

Musculoskeletal Tuberculosis of the Pectoralis With Bilateral Pleural Base Nodular Lesions: A Rare Report of Its Type in an Immunocompetent Female

Chest wall soft-tissue tuberculosis: A case report

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