Primary syphilis: An uncommon manifestation in the oral cavity

Fregnani, Eduardo Rodrigues; Pérez‐de‐Oliveira, Maria Eduarda; Parahyba, Cláudia Joffily; Perez, Danyel Elias da Cruz

doi:10.1016/j.jfma.2016.07.004

Cited by 14 publications

(16 citation statements)

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“…In addition, a small percentage of students reported knowledge about the differential diagnoses of oral manifestations of the disease. Indeed, studies have shown that the diagnosis of oral manifestations of syphilis represents a challenge for professionals because they have a variety of clinical appearances [23,24]. The fact that some characteristics may be similar to other conditions is of concern, and if diagnosis is not performed in the primary and secondary stages, the patient is exposed to the risk of complications related to the tertiary stage [23].…”

Section: Discussionmentioning

confidence: 99%

Knowledge about syphilis and its oral manifestations among dental students: a cross-sectional study from Brazil, 2019

Filho

Garbín

Pires

et al. 2020

Preprint

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Background: Clinical manifestations of the syphilis can occur in the mouth and in the perioral region. This study aimed to investigate the knowledge about syphilis and its oral manifestations among dental students and to discuss the role of the dentist in prevention and control of this disease. Methods: This is a cross-sectional study carried out with 171 dentistry students enrolled in the second, third, fourth and fifth years in the first semester of 2019 from the Federal University of Espírito Santo, Brazil. Data collection was performed by a questionnaire containing 16 questions answered by students in classroom. Analyses of absolute and relative frequency were performed. To perform association among variables, the Chi-square test (or Fisher's exact test with Yates correction) was performed with 5% significance level. Results: Overall, 169 students participated in the study. Only 40 (46.4%) students correctly answered the question about disease stages. Almost all participants answered that syphilis has oral manifestations; however, only 44 (25.7%) answered the question correctly. Regarding differential diagnoses of other oral lesions, only 63 (37.3%) reported knowledge on this subject. There was a statistically significant association between student’s educational level and knowledge about the etiological agent (p<0.0001), clinical manifestations (p<0.0001), disease stages (p<0.0001), oral manifestations (p<0.0001) and drugs (p = 0.005) related to the disease. Conclusions: Participants showed important gaps in their knowledge about syphilis and its oral manifestations. Our findings, together with the increased number of new cases of the disease in the world, reinforce the need for training dental professionals with knowledge about early diagnosis, effective treatment and follow-up of syphilis cases.

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Section: Discussionmentioning

confidence: 99%

Knowledge about syphilis and its oral manifestations among dental students: a cross-sectional study from Brazil, 2019

Filho

Garbín

Pires

et al. 2020

Preprint

View full text Add to dashboard Cite

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“…They manifest as a single ulcer, usually on the lip or more rarely on the tongue 3 . Oral chancres are observed in approximately 4% to 12% of patients with primary syphilis, located where the bacteria penetrate the mucosa 6 .…”

Section: Dear Editormentioning

confidence: 99%

“…The clinical diagnosis of syphilis is challenging for the dentist due to the variety of clinical characteristics of oral lesions, which may be similar to other ulcerative injuries 6 . The differential diagnosis of oral lesions of secondary syphilis includes erythematous lupus, multiform erythema, stomatitis, pemphigus, idiopathic leukoplakia, lichen planus, and candidiasis, among others 9 .…”

Section: Dear Editormentioning

confidence: 99%

The dentist’s role in syphilis prevention and control

Garbín

Filho

Garbín

et al. 2019

Rev. Soc. Bras. Med. Trop.

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“…Clínicamente, la manifestación oral de la sífilis puede parecerse a otras entidades, lo que dificulta el diagnóstico correcto por lo que debe tenerse en cuenta en el diagnóstico diferencial de las lesiones ulcerosas orales en los pacientes sexualmente activos [7,9]. La sífilis primaria puede observarse en la cavidad oral, y se ha asociado con el sexo oral [10,11]. El chancro de inoculación de la sífilis primaria puede ocurrir en la boca y región perioral pero es infrecuente (sólo 8 % de los casos) [12][13][14][15].…”

Section: Palabrasunclassified