Primary Synovial Sarcoma of the Parietal Pleura: A Case Report

Abstract

Synovial sarcoma is a malignant soft tissue tumor that most commonly occurs in the extremities of young and middle-aged adults, in the vicinity of large joints. Although synovial sarcoma is frequently associated with joints, it may arise in unexpected sites, such as the mediastinum, heart, lung, pleura, or chest wall. Primary synovial sarcoma of the pleura is rare. To date, nearly 36 cases of primary synovial sarcoma of the pleura have been reported since Gaertner et al. published the first case in 1996. The oncologic characteristics, treatment, and prognosis for pleural synovial sarcomas are not well defined because of a paucity of data. However, a multimodal approach, including surgical resection, chemotherapy, and radiotherapy, has generally been suggested. We report the outcome of one patient with primary pleural synovial sarcoma treated with radical resection and adjuvant treatment.

Primary Synovial Sarcoma of Lung

“…SS can also arise from the pleura. However, primary SS of the pleura is also very rare and there are a limited number of reported cases [ 8 ]. Our case presented with a centrally located tumor and a complaint of chest pain.…”

Extensive surgical resections for rare pleural neoplasms: A single-center experience with a yolk sac tumor and synovial sarcoma.

“…(18) Since then, few cases have been reported by others. (17,(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29) A range of treatments have been suggested for pleural synovial sarcoma including extensive surgical resection, (neo)adjuvant chemotherapy (with ifosfamide and doxorubicin), and radiotherapy. (19,(24)(25)(26)(28)(29)(30)(31) Complete surgical resection appears to be associated with improved survival outcomes.…”

Plevral sinoviyal sarkom: Olgu sunumu

“…Bugüne kadar 1996 yılında Gaertner ve ark. 'ın 4 sunduğu ilk vakadan beri yaklaşık 37 vaka bildirilmiştir. Bizim olgumuzda nadir görülen bir plevral sinoviyal sarkom vakası idi.…”

“…Cerrahi rezeksiyon ile birlikte uygulanacak radyoterapi ve kontrol edilemeyen olgularda kemoterapi sağ kalımı uzatabilse de, multipl rekürrens gözlenebilmektedir. 3,4,9 Bir metaanalizde komplet rezeksiyonun en etkin prognostik faktör olduğu belirtilmiştir. Aynı zamanda bu meta-analizde komplet cerrahi rezeksiyonu takiben adjuvan radyoterapi ve adjuvan kemoterapi uygulaması lokal nüks gözlenme süresini ve rekürrenssiz surveyi ve dolaylı olarak sağ kalım oranını arttırdığı belirtilmiştir.…”