Primary solitary lymphoma of the trachea

Pradhan, Duleep J.; Rabuzzi, Daniel D.; Meyer, John W.

doi:10.1016/s0022-5223(19)39677-1

Cited by 20 publications

(6 citation statements)

References 4 publications

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“…Primary malignant lymphoma of the trachea and subglottic region is extremely rare; only one similar case report (6) could be found. Furthermore, there were four reported cases of primary subglottic lymphoma in the Japanese literature (4) and three cases of primary tracheal lymphoma in the English language literature (1)(2)(3). Thus, there is little conclusive information on the pathogenesis and treatment for this disease.…”

Section: Discussionmentioning

confidence: 99%

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Primary Malignant Lymphoma of the Trachea and Subglottic Region.

et al. 1992

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A 44-year-old female was admitted with the complaint of choking. On fiberbronchoscopic examination, multiple, polypoid lesions with a smooth surface were exhibited at the cervical trachea. Histological diagnosis was B-cell malignant lymphoma, diffuse, medium sized cell type (LSG classification). No other lesions were detected in the systemic evaluation. After combined chemotherapy and regional irradiation, the tumor disappeared. The clinical and pathological characteristics of this case are similar to those of malignant lymphoma of mucosa-associated lymphoid tissue (MALT).

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Section: Discussionmentioning

confidence: 99%

“…There are a few reports of primary malignant lym phoma of the trachea (1)(2)(3) and the larynx (4)(5)(6)(7). Re cently, Isaacson et al proposed the entity of malignant lymphoma of mucosa-associated lymphoid tissue (MALT) which shows a favorable clinical course and similar pathological findings (8-10).…”

Section: Introductionmentioning

confidence: 99%

Primary Malignant Lymphoma of the Trachea and Subglottic Region.

et al. 1992

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“… 6 In a review of the English literature, there are only nine cases of tracheal NHL described until now. 1–9 Although their clinical course changed widely, the most common presenting clinical features were dyspnea, wheezing and cough. Diagnosis was frequently delayed because of the lack of specific symptoms or signs indicative of tracheal disease.…”

Section: Discussionmentioning

confidence: 99%

“…The cells were small and round with a moderate amount of eosinophilic cytoplasm. The nuclei were devoid of pleomorphism, and mitotic index was scant (0.5–1 mitosis/mm 2 ).…”

Section: Pathological Findingsmentioning

confidence: 99%

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Primary lymphoplasmacytoid lymphoma of the trachea with immunoglobulin G paraprotein

Gómez-Román¹,

Pérez‐Montes

Pérez‐Expósito³

et al. 1999

Pathology International

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A primary tracheal lymphoma with immunoglobulin G (IgG)-associated monoclonal serum paraprotein treated with surgery and chemotherapy is reported. As far as we know this is the first lymphoplasmacytoid lymphoma reported in the tracheobronchial tree and the first with a serum and tissue IgG monoclonal paraprotein. Differential diagnosis must be made essentially with extramedullary plasmacytoma and mucosa-associated lymphoid tissue lymphoma. CD-45RB strong positivity and the absence of lymphoepithelial lesions may help to differentiate lymphoplasmacytoid lymphoma from them. We expand the spectrum of lymphoid lesions with plasmacytoid features that can occur in the tracheobronchial tract.

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Primary tracheal non-Hodgkin's lymphoma: A case report and review of the literature

Fidias

Wright

Harris

et al. 1996

Cancer

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BACKGROUND. Primary tracheobronchial non-Hodgkin's lymphoma (NHL) is an uncommon occurrence. The authors report a patient who presented with primary tracheal NHL, the sixth such patient described in the literature. METHODS. Using a MEDLINE search, 41 additional patients presenting with symptomatic primary or secondary tracheobronchial NHL were identified. The characteristics, management, and outcome of these patients are described. RESULTS. Patients with NHL of the upper respiratory tract present with dyspnea, wheezing, and cough, and frequently are misdiagnosed as having asthma. The majority of patients have additional sites of intrathoracic disease with tracheobronchial involvement occurring in the setting of advanced or relapsed NHL. Low grade histology is seen most commonly in patients with primary tracheal NHL. Several patients demonstrate the typical histologic features of mucosa-associated lymphoid tissue. Surgery, chemotherapy, and radiation therapy have been used alone or in combination for treatment. The outcome of these patients does not appear different from that observed in patients with lymphomas of similar histology and stage that do not involve the tracheobronchial tree. CONCLUSIONS. Thoracic surgeons, pulmonologists, and oncologists should recognize that NHL can rarely be confined to the trachea or bronchi. NHL should be considered in the differential diagnosis of airway obstruction, because it represents a highly treatable malignancy.

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Primary solitary lymphoma of the trachea

Cited by 20 publications

References 4 publications

Primary Malignant Lymphoma of the Trachea and Subglottic Region.

Primary Malignant Lymphoma of the Trachea and Subglottic Region.

Primary lymphoplasmacytoid lymphoma of the trachea with immunoglobulin G paraprotein

Primary tracheal non-Hodgkin's lymphoma: A case report and review of the literature

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