Primary retroperitoneal mucinous cystadenocarcinoma: report of two cases

León, David Cantú de; Pérez-Montiel, Delia; Chanona-Vilchis, José; Dueñas‐González, Alfonso; Villavicencio-Valencia, Verónica; Zavala-Casas, Gladys

doi:10.1186/1477-7819-5-5

Cited by 38 publications

(30 citation statements)

References 10 publications

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“…Approximately 33 cases of cystadenomas, 35 cases of cystadenocarcinoma and nine cases of borderline malignancy have been published in the literature to date. These tumours have been described exclusively in females; however, very rarely, they have been described in male patients [4,5].…”

Section: Discussionmentioning

confidence: 99%

“…The precise aetiology of these neoplasms is uncertain and various theories have been proposed [3]. In the majority of instances, preoperative diagnosis is not possible, as radiological findings are not able to distinguish the exact nature and origin of these lesions [4]. A definitive diagnosis can only be made after complete surgical excision and histological examination, having excluded retroperitoneal involvement by mucinous tumours from sites such the ovaries, bowel, appendix and pancreas.…”

Section: Introductionmentioning

confidence: 99%

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Primary retroperitoneal cystic mucinous borderline tumour mimicking an ovarian neoplasm: a case report and literature review

Nasir¹,

Nair²,

Faulkner³

et al. 2008

Gynecol Surg

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Ovarian-type mucinous tumours occur very rarely in the retroperitoneum. We present a case of primary retroperitoneal mucinous tumour of borderline malignancy in a 58-year-old woman, detected as an incidental finding. The patient presented with acute renal failure, investigation for which revealed a complex pelvic mass initially thought to be in the right adnexa and consistent with an ovarian neoplasm. Surgical findings revealed a 130-mm, right-sided non-communicating retroperitoneal pelvic mass, posterior to the appendix, which was completely resected. Both ovaries were normal. Macroscopically, it was a multiloculated cystic structure with a smooth external surface containing clear and mucinous fluid. Microscopic examination showed a mucinous tumour of borderline malignancy. The literature contains approximately nine other cases of primary mucinous retroperitoneal tumour of borderline malignancy. These cases have occurred in women aged 36-60 years. Most patients were asymptomatic and the mass was detected as an incidental finding. The patients have been followed up for up to 6 to 18 months and, to date, none have recurred. There are limitations to pre-operative radiological imaging. A definitive diagnosis can only be made after complete surgical excision and histological examination, having excluded retroperitoneal involvement by mucinous tumours from sites such the ovaries, bowel, appendix and pancreas.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Primary retroperitoneal cystic mucinous borderline tumour mimicking an ovarian neoplasm: a case report and literature review

Nasir¹,

Nair²,

Faulkner³

et al. 2008

Gynecol Surg

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“…The most frequent presentations of the metastatic disease were a pelvic mass (4 patients) [14,15,21,22] and multiple liver lesions (3 patients; table 3) [14,17]. In this setting, the most common approach was the rescue surgery (5 patients) [15,17,21,22,30]; 2 women were treated with chemo-radiotherapy instead (table 2) [3,59].…”

Section: Resultsmentioning

confidence: 99%

“…In this setting, the most common approach was the rescue surgery (5 patients) [15,17,21,22,30]; 2 women were treated with chemo-radiotherapy instead (table 2) [3,59]. After the progression of the metastatic disease, some authors re-operated their patients [15,21], others administered a hormonal treatment [21,22] like tamoxifen or chemotherapy (table 2) [21,30,59]. …”

Section: Resultsmentioning

confidence: 99%

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Primary Retroperitoneal Cystoadenocarcinoma: A Systematic Review

Pellegrino

Sikokis²,

Bersanelli³

et al. 2016

Gynecol Obstet Invest

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Background/Aims: The aim of this study was to perform a systematic review on primary retroperitoneal cystoadenocarcinoma (PRC), which is an extremely rare disease. Methods: According to PRISMA guidelines, all the literature about PRC from 1977 to 2015 was reviewed. Thirty articles were selected; characteristics of the patients were collected and described; time to recurrence and overall survival (OS) were investigated when available. Results: Thirty seven patients were included of whom 33 were females; the median age at presentation was 43. PRC was more common in postmenopausal women. Surgery was the standard therapy; the role of chemotherapy and/or radiotherapy was uncertain. Thirty percent of the patients relapsed after 58 months from the surgery; the rupture of the cyst occurred in 13% of the cases and it was associated with poor prognosis as well as premenopausal status. At 125 months from the diagnosis, 72% of the patients were alive and the median OS was not reached. Conclusions: The present systematic review about PRC is the first performed until the date of drafting this paper. We described some clinical features of PRC and their possible prognostic value. No conclusive data can be presented due to the small population analyzed and to publication bias.

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Primary retroperitoneal mucinous cystadenocarcinoma with transition from the mesothelium

et al. 2020

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Introduction Mucinous cystic neoplasms are uncommon among the tumors that develop in the retroperitoneum. We report a case of primary retroperitoneal mucinous cystadenocarcinoma with pathological considerations. Case presentation A 47‐year‐old woman complaining of abdominal discomfort presented at our hospital. Abdominal computed tomography and magnetic resonance imaging showed a large cystic tumor with small solid nodules located in the right retroperitoneum. The tumor was completely removed and the microscopic findings were consistent with primary retroperitoneal mucinous cystadenocarcinoma. Two years after the surgery, the patient is alive without recurrence of the tumor. Conclusion The microscopic findings suggested that the primary retroperitoneal mucinous cystadenocarcinoma developed from the metaplasia of the remnant coelomic epithelium. A complete tumor resection that includes the adjacent peritoneum is important to prevent local recurrence.

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Primary retroperitoneal mucinous cystadenocarcinoma: report of two cases

Abstract: The behavior and treatment of retroperitoneal cystadenocarcinoma are controversial. We suggest aggressive surgery including radical hysterectomy and bilateral salpingoopherectomy with adjuvant chemotherapy in these cases.

Cited by 38 publications

References 10 publications

Primary retroperitoneal cystic mucinous borderline tumour mimicking an ovarian neoplasm: a case report and literature review

Primary retroperitoneal cystic mucinous borderline tumour mimicking an ovarian neoplasm: a case report and literature review

Primary Retroperitoneal Cystoadenocarcinoma: A Systematic Review

Primary retroperitoneal mucinous cystadenocarcinoma with transition from the mesothelium

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