Primary pure squamous cell carcinoma of the breast diagnosed by fine‐needle aspiration cytology: A case study using liquid‐based cytology

Vera-Alvarez, J; García-Prats, María Dolores; Marigil-Gómez, Miguel; Abascal-Agorreta, Manuel; López-López, José Ignacio; Ramón-Cajal, José Manuel

doi:10.1002/dc.20658

Cited by 8 publications

(7 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, CT imaging in our case did not identify multiple lesions or lymphadenopathy of the axilla. Fine-needle aspiration cytology has been reported to successfully identify both primary and metastatic malignancies of the breast [10,14]. Excisional or core biopsy is usually needed for final pathological confirmation, as in our case.…”

Section: Discussionmentioning

confidence: 66%

Squamous cell carcinoma of the hand metastasized to the breast: A unique case

Galyfos

Karantzikos

Sianou

et al. 2014

View full text Add to dashboard Cite

Metastatic squamous cell carcinoma (SCC) to the breast is a very rare entity with a few cases reported in the literature, while the hand as an extra-mammary origin site for this type of malignancy has not been reported before. We describe a unique case of a woman with a SCC lesion excised from the right index finger that metastasized to her ipsilateral breast. A 68-year-old female patient presented with a small palpable lesion of the right breast and without any skin ulceration or malformation. Ultrasonography and computed tomography studies revealed a solitary metastatic lesion of the breast, without any multiple disease or lymphadenopathy diagnosed. Fine Needle Aspiration (FNA) cytology confirmed the correlation of the lesion with the primary site. The patient underwent further surgical and oncological management. The use of FNA cytology is important to distinguish a metastasis from primary breast cancer in order to avoid unnecessary conflicting treatments, even when the medical history is not typical or revealing. SCCs of the hand can give metastases to unusual sites such as the breast and must always be closely followed-up, even if they are successfully excised in healthy margins originally.

show abstract

Section: Discussionmentioning

confidence: 66%

Squamous cell carcinoma of the hand metastasized to the breast: A unique case

Galyfos

Karantzikos

Sianou

et al. 2014

View full text Add to dashboard Cite

show abstract

“…The neoplastic cells infiltrate the adjacent stroma and an increase in size occurs on follow-up. Among the reported cases of squamous cell carcinoma of the breast, the diagnosis using FNAS was different: benignity or malignancy [11,12]. This difference was caused by the difficultly in the evaluation of the atypia of squamous epithelium, and so if RCBM is used for such tumors, it provides a precise evaluation of the atypical status of squamous epithelium and relationship between the atypical epithelium and stroma, leading to a precise diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Combined Core Needle Biopsy and Fine Needle Aspiration Cytology Using Returned Cell Block Method is Effective for Diagnosis of Cystic Lesions of the Breast

Kosaka¹,

Azami²,

Iino³

et al. 2017

J Cytol Histol

View full text Add to dashboard Cite

Background: Core needle biopsy (CNB) and fine needle aspiration cytology (FNAC) are useful methods to diagnose cystic lesions of the breast. The first English article describing the returned cell block method (RCBM: cell block from a Papanicolaou staining smear on a glass slide) was reported by us, and we also reported the usefulness of RCBM for the FNAC-based evaluation of tumors of the breast. In the present study, diagnostic procedures of CNB and FNAC using RCBM for cystic lesions of the breast were studied.

show abstract

“…Squamous cells are normally not found inside the breast, so a PSCCB is an exceptional phenomenon. [1][2][3][4][5][6][7][8] Until 2010, only 100 cases of PSCCB have been reported. [9] The World Health Organization categorized these tumor as a metaplasia carcinoma.…”

Section: Discussionmentioning

confidence: 99%

“…metastasis of a squamous cell carcinoma somewhere else in the body and squamous metaplasia in ductal carcinoma of breast are the key for specifi c diagnosis and management. [1,4,[6][7][8]10,11] The management and prognosis of PSCCB is still controversial. [2,4,5,7] We report a case of PSCCB in a 52-year-old woman, with discussion of cytology, and histology fi ndings.…”

Section: Primary Squamous Cell Carcinoma Of the Breast: A Cytological...mentioning

confidence: 99%

See 1 more Smart Citation

Primary squamous cell carcinoma of the breast: A cytological and histological correlation

Nasit

Dhruva

2013

Clin Cancer Investig J

View full text Add to dashboard Cite

Primary squamous cell carcinoma of the breast (PSCCB) is an extremely rare disease. Origin is controversial; it is thought to arise through the metaplasia of various benign and malignant breast lesions. It usually present with rapidly growing large mass, otherwise similar to that of ductal breast carcinoma. Fine needle aspiration cytology (FNAC) is an accurate and safe diagnostic procedure for breast malignancies. However, cytologists are still facing some difficulties in specific diagnosis of various subtypes of breast malignancy.Extensive squamous cells on cytology should be evaluated with the great caution. Ductal breast carcinoma with squamous metaplasia, squamous carcinoma of the breast skin, and metastasis from non-mammary tissues should be consider before the making the diagnosis of PSCCB. Specific management and prognosis of PSCCB is still debatable. We present a case of 52-year-old woman with a breast mass. FNAC revealed predominantly clusters and dispersed malignant squamous cells, without any ductal cells, suggest PSCCB; possibility of secondary or ductal breast carcinoma with squamous metaplasia should be ruled out. After modified radical mastectomy histology confirmed the diagnosis of PSCCB. Post-operative cisplatin and 5-fluouracil were administered. Patient is disease free at 12 months of follow-up.

show abstract

Primary pure squamous cell carcinoma of the breast diagnosed by fine‐needle aspiration cytology: A case study using liquid‐based cytology

Cited by 8 publications

References 10 publications

Squamous cell carcinoma of the hand metastasized to the breast: A unique case

Squamous cell carcinoma of the hand metastasized to the breast: A unique case

Combined Core Needle Biopsy and Fine Needle Aspiration Cytology Using Returned Cell Block Method is Effective for Diagnosis of Cystic Lesions of the Breast

Primary squamous cell carcinoma of the breast: A cytological and histological correlation

Contact Info

Product

Resources

About