Primary plasmacytoma of the testicle: a case report

Berrondo, Claudia; Gorman, Timothy; Yap, Ronald L.

doi:10.1186/1752-1947-5-494

Cited by 9 publications

(7 citation statements)

References 9 publications

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“…On gray-scale ultrasound, plasmacytoma of the testicle appears hypoechoic that can either be heterogeneous or homogeneous (8)(9)(10)(11)(12). Bude (10) noticed that the hyperemia of a plasmacytoma is much greater than usual experience with testicular germ cell neoplasms and similar to hyperemia seen in testicular lymphoma or leukemia.…”

Section: Discussionmentioning

confidence: 96%

Testicular plasmacytoma, an unusal testicular tumor

Roels¹,

Mattelaere

Claikens

2014

Journal of the Belgian Society of Radiology

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We report the case of a 78-year-old man with recent diagnosis of Kahler disease and a non-tender swollen left hemiscrotum. ultrasound findings showed an intratesticular, hypervascular hypoechoic lesion. mri imaging demonstrated general appearance of a malignant lesion. specific characteristics however, could not be withheld on mri. orchidectomy was performed and plasmacytoma was demonstrated at pathological examination. although plasmacytoma of the testis is extremely rare, it should be included in the differential diagnosis taking into account the ultrasound and mri appearances, especially in elderly patients with known Kahler disease. Key-word: plasmocytoma.From: Dept of 1. Radiology and 2. Urology, AZ Damiaan, Oostende, Belgium.

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Section: Discussionmentioning

confidence: 96%

Testicular plasmacytoma, an unusal testicular tumor

Roels¹,

Mattelaere

Claikens

2014

Journal of the Belgian Society of Radiology

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“…Reducing tumor mass without a R0‐claim (no residual tumor remaining) may only be performed if it allows a rapid elimination of local symptoms (e.g., respiratory disability) and the effects of radiation therapy cannot be waited for. For most EMPs in the UAD region, surgery is not the best choice of treatment, as it may lead to serious mutilation 17,24–28 . In line with these considerations, the absolute numbers of surgeries as a sole treatment of EMP decreased in UAD regions, although this sole therapy approach remained among the three most commonly administered therapies in the UAD.…”

Section: Discussionmentioning

confidence: 99%

“…In EMP, there is normally no indication for chemotherapy, even if local lymph nodes are involved 17,24,38 . However, in case of large tumors, chemotherapy should be considered after radiotherapy, especially when the tumor is larger than 5 cm 26,39 .…”

Section: Discussionmentioning

confidence: 99%

Extramedullary plasmacytoma: Tumor occurrence and therapeutic concepts—A follow‐up

et al. 2022

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Background Extramedullary plasmacytoma (EMP) is a solitary tumor consisting of neoplastic plasma cells, with very little to no bone marrow involvement. EMPs are usually located in the head and neck region, but can also occur along the digestive tract, in lungs, or extremities. Methods Following our publication on EMP, which appeared in 1999 (Cancer 85:2305–14), we conducted a literature search for EMP‐related reports published between 1999 and 2021. The documented cases, as well as 14 of our own patients from the ENT Clinic Erlangen, were extensively analyzed. Results Between 1998 and 2021, 1134 patients with EMP were reported, for whom information about the tumor localization was available. Among those, 62.4% had EMP in the head and neck area and 37.6% in other body regions. Data on therapy were reported in 897 patients, including 34.3% who received radiation, 28.1% surgery, 22.6% a combination of surgery and radiation, and 15.9% another therapy. In 76.9% patients no recurrence or transformation to multiple myeloma (MM) was reported, 12.8% showed local recurrence and 10.2% developed MM. Radiotherapy alone was associated with a tendency for increased occurrence of MM. In patients with EMP of head and neck area, combination therapy (surgery and radiation) resulted in a 5‐year overall survival rate of 98.3%, surgery alone of 92.4%, and radiotherapy of 92.7%. Conclusions Collectively, our analyses indicate that surgical resection alone can achieve long‐term tumor control in patients with EMP, if the tumor can be removed within safe limits without causing serious functional impairment. However, if this is not certain, either radiation or a combination of surgery and radiation therapy is suggested as an effective means of local tumor control.

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“… Testicular plasmacytomas in the literature and their underlying diagnosis[ 13 14 16 18 19 21 22 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 ] …”

Section: Discussionmentioning

confidence: 99%

Plasmacytoma of the testis in a patient with relapsed and refractory multiple myeloma: Case report and review of the literature

et al. 2015

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Testicular plasmacytoma, whether occurring as a primary lesion or as a reflection of underlying multiple myeloma (MM), is a rare disease. We report the case of a 38-year-old male with multiply relapsed MM, who was found to have a testicular plasmacytoma. He presented with a gradually enlarging scrotal mass. Following orchidectomy, pathologic examination of the specimen demonstrated a plasmacytoma. In the context of active MM, the specimen was also sent for cytogenetic analysis but this was unhelpful in guiding a chemotherapy regime, which still continues at time of reporting. Although a rare lesion, there remains no definitive treatment protocol for the management of testicular plasmacytoma representing an extramedullary manifestation of MM.

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Primary plasmacytoma of the testicle: a case report

Cited by 9 publications

References 9 publications

Testicular plasmacytoma, an unusal testicular tumor

Testicular plasmacytoma, an unusal testicular tumor

Extramedullary plasmacytoma: Tumor occurrence and therapeutic concepts—A follow‐up

Plasmacytoma of the testis in a patient with relapsed and refractory multiple myeloma: Case report and review of the literature

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