Primary percutaneous coronary intervention for ST elevation myocardial infarction in octogenarians: trends and outcomes

Abstract

Primary percutaneous coronary intervention for ST elevation myocardial infarction in octogenarians: trends and outcomes Claessen, B.E.P.M.; Kikkert, W.J.; Engstrom, A.E.; Hoebers, L.P.; Damman, P.; Vis, M.M.; Koch, K.T.; Baan, J.,Jr; Meuwissen, M.; van der Schaaf, R.J.; de Winter, R.J.; Tijssen, J.G.; Piek, J.J.; Henriques, J.P. General rightsIt is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulationsIf you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: http://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. In the total cohort of 379 patients, 30-day mortality was 21% (81 patients) and 1-year mortality was 28% (107 patients). There was no improvement in survival among octogenarian STEMI patients over the 11-year study period. Conclusion The annual proportion of octogenarian STEMI patients increased significantly over the 11-year study period. Mortality among these high-risk patients was high and did not improve during the study period. Unfortunately, little is known about the optimal treatment of the elderly as they are underrepresented in many randomised clinical trials. Further studies into the optimal STEMI management strategy for the elderly are warranted.

In‐hospital outcomes of very elderly patients (85 years and older) undergoing percutaneous coronary intervention

“…In our study mortality following primary PCI was 18.2% and MACE 22.7%, although the absolute numbers in both cohorts were small (only 2.5% of all procedures in patients younger than 85 years, and 5.5% of those aged 85 years and older), explained by the absence of a 24Â7 primary PCI program at our center until mid-2008. Claessen et al report a 30-day mortality of 21% in 379 octogenerians undergoing primary PCI between 1997 and 2007 [26]. The Senior PAMI study randomized 483 patients older than 70 years to primary PCI versus thrombolysis, including a subgroup of 130 patients aged 80 years or older.…”

The Reduction of Hospital Mortality of Myocardial Infarction in «problem Groups» – Focus on Patients Over 75 Years

“…Первая особенность -это естественные многочисленные изменения функционального состояния организма, которые характеризуют-ся гармоничным снижением функций органов и систем, метаболизма, а также реактивности [10]. Вторая особенность связана с полиморбидно-стью, которая не только затрудняет диагностику, но и приводит к взаимоотягощающему течению заболеваний [7]. Третьей особенностью является течение острых коронарных состояний с рядом клинических проявлений, отличных от группы более молодых пациентов [11,12].…”

“…В иностранной литературе изучают больных старше 80 лет и реже старше 90 лет [7][8][9]. По ана-логии в нашей стране для своих исследований в редких случаях используется критерий «старше 80 лет».…”

Short and long term outcomes of primary angioplasty in patients aged 75 years and over

“…Bir yıllık MKOO oranları ise bizim çalışmamızda %28 iken, diğer çalışmalarda sırasıyla %16-%24.3-%28 idi. 1,11,12 Farklı çalışmalarda farklı MKOO oranlarının bulunmasına rağmen tüm çalışmalarda dikkati çeken husus, hastane içi MKOO' ın bir yıllık MKOO'ın büyük bir kısmını oluşturuyor olmasıydı. Farklı ça-lışmalarda farklı sonuçlara varılmasının nedeniyse; hasta profillerinin farklılığına ve merkezlerin primer PKG konusundaki deneyimlerindeki farklılığa bağlandı.…”