Primary Paratesticular Epithelioid Leiomyosarcoma

Ptochos, A.; Iosifidis, N.; Papazafiriou, G.; Kehagia-Koutoufari, T.; Karagiannopoulou, Georgia

doi:10.1159/000070143

Cited by 5 publications

(1 citation statement)

References 9 publications

(9 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Scrotal leiomyosarcoma could grow in various histopathological variants (e.g. epithelioid leiomyosarcoma), but it is believed that it does not affect prognosis of these tumors more than grading or staging [10]. Tumor grading strictly affects prognosis since well differentiated, low grade (G1) leiomyosarcomas are completely curable by local excision, while all poorly differentiated (G3) leiomyosarcomas resulted in death of the patients [11].…”

Section: Discussionmentioning

confidence: 99%

Role of immunohistochemical and histochemical profiling in H&E-based diagnosis of scrotal leiomyosarcoma of dartos muscle

Wincewicz

Lewitowicz²,

Sulkowska³

et al. 2014

Folia Histochem Cytobiol.

View full text Add to dashboard Cite

Histochemical and immunohistochemical methods should often but not always complement standardized histopathologic procedures. Here, we illustrate use of these ancillary techniques in a report of scrotal leiomyosarcoma. 62-year-old male patient presented with a palpable, subcutaneous 2,5 cm wide tumor arising from dartos muscle. The tumor was diagnosed leiomyosarcoma G2 pT1b. Interestingly, the sarcomatous mass was focally strictly attached to convoluted, benign bundles of smooth muscles that were intermingled with tumor mass at peripheral, lateral and superior sides of the lesion. We have used immune-and histochemical methods to confirm histopathological findings based on H&E staining. As expected, in tumor cells smooth muscle actin and desmin were strongly immunopositive similarly as Masson trichrome staining, while S100 and CD34 antigens were immunonegative except for sustained positivity for CD34 in vessels. The auxiliary staining methods can provide additional information on the tumorigenesis of leiomyosarcoma. They can also serve to determine additional features of prognostic significance, since e.g. immunoreactivity of CD34 accurately maps vascular density of tumor and enables a careful assessment of vascular invasion in course of leiomyosarcoma as well.

show abstract

Section: Discussionmentioning

confidence: 99%

Role of immunohistochemical and histochemical profiling in H&E-based diagnosis of scrotal leiomyosarcoma of dartos muscle

Wincewicz

Lewitowicz²,

Sulkowska³

et al. 2014

Folia Histochem Cytobiol.

View full text Add to dashboard Cite

show abstract

Rémission complète d’un sarcome intratesticulaire

2009

View full text Add to dashboard Cite

Ré publique du Congo 2 Service d'anatomie et cytologie pathologiques, centre hospitalier et universitaire de Brazzaville, BP 32, Brazzaville, Ré publique du Congo Correspondance : drjmalandam@yahoo.fr Reç u le 4 mars 2008 ; accepté le 28 novembre 2008Complete remission of an intra-testicular sarcoma Abstract: Two cases of testicular sarcoma were encountered in Brazzaville university hospital. The first consisted of a 41-year old man who was admitted in the polyvalent surgeon unit for an enlarged testicle. He underwent left orchiectomy. He did not come back for his regular visit 8 months later. The second patient was a young man of 21 years who was seeking care for an increase of his left testicle seen eight months before. He underwent left orchiectomy and according to the histopathologic evaluation, he had a testicular spindle cells sarcoma. Three months after surgery, the patient showed an alteration of his general state while liver metastases and left hydronephrosis were observed. Chemotherapy with vincristin and cisplatin was initiated. Complete remission was seen after three cycles of chemotherapy, with the disappearance of liver metastases and the restoration of a good general health status until 28 months after surgery in 30 June 2008.

show abstract

Leiomiosarcoma paratesticular de larga evolución. Revisión conceptual y de la literatura

Liso¹,

García

López³

et al. 2008

Actas Urológicas Españolas

View full text Add to dashboard Cite

The long evolution of a paratesticular tumour and the absence of metastasis does not exclude its malignancy. The low incident of the LMSs in this location, implies that a protocol of actuation validate for such does not exist. We considered of great importance, its creation on the part of urologist, oncologists, radiologists and pathologists like he took control of located in retroperitoneal cavity and deep soft tissues.

show abstract

Primary Paratesticular Epithelioid Leiomyosarcoma

Cited by 5 publications

References 9 publications

Role of immunohistochemical and histochemical profiling in H&E-based diagnosis of scrotal leiomyosarcoma of dartos muscle

Role of immunohistochemical and histochemical profiling in H&E-based diagnosis of scrotal leiomyosarcoma of dartos muscle

Rémission complète d’un sarcome intratesticulaire

Leiomiosarcoma paratesticular de larga evolución. Revisión conceptual y de la literatura

Contact Info

Product

Resources

About