Primary Open-angle Glaucoma, Intraocular Pressure, and Diabetes Mellitus in the General Elderly Population

Dielemans, Ida; Jong, Paulus T. V. M. de; Stolk, Ronald P.; Vingerling, Johannes R.; Grobbee, Diederick E.; Hofman, Albert

doi:10.1016/s0161-6420(96)30511-3

Cited by 238 publications

(178 citation statements)

References 18 publications

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“…Although the eyes of diabetics (all type 2) had higher IOPs (a mean of 0.4 mmHg higher) in our study, this did not reach statistical significance in contrast to the results of larger comparative studies that included types 1 and 2 diabetics. 27,28 Similar findings of an association between diabetes and thicker CCT have been found in the Barbados Eye Study, 25 and in another study, 29 whereas a Japanese study found no increase in CCT in type 2 diabetic patients. 30 Potential sources of bias exist in our study.…”

Section: Discussionsupporting

confidence: 66%

The relationship between central corneal thickness and the optic disc in an elderly population: the Bridlington Eye Assessment Project

Hawker

Edmunds

Vernon

et al. 2007

Eye

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Purpose To determine population-based normative CCT data for elderly white subjects, with and without diabetes, and to explore the relationship between CCT and IOP and HRT2 measurements in such subjects with normal visual fields. Methods All eligible subjects were consecutive in a population screened for eye disease. CCT was measured by ultrasound pachymetry, and the optic disc was morphometrically defined using Heidelberg retinal tomography (HRT2). Inclusion criteria were: (1) normal visual field on suprathreshold testing and (2) corrected logMAR acuity of at least 0.3 in both eyes. Subjects with significant corneal pathology, previous corneal surgery, or known history of glaucoma or treatment for raised intraocular pressure were excluded. One eye was randomly selected from each subject for analysis. Results In all, 983 eyes of 983 subjects were included with 690 HRT images deemed acceptable for the analysis. The mean age (414 men and 569 women) was 73.3 years (minimum 65 years). Mean (SD) CCT was 544.1 (36.5) lm, with a normally distributed range of 429-633 lm. There was no significant difference in CCT between men and women (mean CCT 546.1 and 542.7 lm, respectively, P ¼ 0.15, Student's t-test), though CCT was correlated weakly and negatively with age (Pearson's r ¼ À0.063, P ¼ 0.047). Diabetic patients (n ¼ 103) had a greater mean CCT than non-diabetic patients (551.9 and 543.0 lm respectively, P ¼ 0.02). No significant correlation was found between any global optic disc parameter and CCT in the 690 eyes analysed. Conclusion Elderly white eyes with normal fields have CCTs that are normally distributed, with those from diabetic persons having greater CCTs. No clear evidence of a relationship between CCT and HRT2 optic disc parameters used in glaucoma diagnosis was found.

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Section: Discussionsupporting

confidence: 66%

The relationship between central corneal thickness and the optic disc in an elderly population: the Bridlington Eye Assessment Project

Hawker

Edmunds

Vernon

et al. 2007

Eye

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“…[100][101][102][103][104] IOP, diabetes and myopia status were obtained from a secure record (examination or examination records) in most studies. However, only one (20%) 105 obtained family history status from a secure source, by examination of firstdegree relatives of detected cases. Sixteen (59%) included studies specified the participation rate to be greater than 75%; however, this information was unclear in seven (26%) studies.…”

Section: Quality Of Available Evidencementioning

confidence: 99%

“…Only A-rated studies are described in this section (n = 19). 21,22,28,63,64,99,[105][106][107][108][109][110][111][112][113][114][115][116][117] All but one of the included studies 105 described a population-based cross-sectional study. The remaining eight studies [100][101][102][103][104][118][119][120] are also described in Appendix 6.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

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The clinical effectiveness and cost-effectiveness of screening for open angle glaucoma: a systematic review and economic evaluation

Burr¹,

Mowatt²,

Hernández³

et al. 2007

Health Technol Assess

327

380

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“…Concluiu-se, apesar de nossa pequena amostra, que o nível de conhecimento de pacientes com diagnóstico de glaucoma é extremamente baixo comparado com o número de pacientes com suspeita de terem hipertensão ou diabete e principalmente comparado com o conhecimento de pacientes de países desenvolvidos (8)(9)(10)(11)(12)(13) .…”

Section: Discussionunclassified

Estudo dos conhecimentos de pacientes com hipertensão, diabetes ou glaucoma sobre suas doenças

Sakata¹,

Bigolin²,

Bryk³

et al. 2002

Arq. Bras. Oftalmol.

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Primary Open-angle Glaucoma, Intraocular Pressure, and Diabetes Mellitus in the General Elderly Population

Cited by 238 publications

References 18 publications

The relationship between central corneal thickness and the optic disc in an elderly population: the Bridlington Eye Assessment Project

The relationship between central corneal thickness and the optic disc in an elderly population: the Bridlington Eye Assessment Project

The clinical effectiveness and cost-effectiveness of screening for open angle glaucoma: a systematic review and economic evaluation

Estudo dos conhecimentos de pacientes com hipertensão, diabetes ou glaucoma sobre suas doenças

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