Primary Neoplasms of the Appendix Manifesting as Acute Appendicitis: CT Findings with Pathologic Comparison

Pickhardt, Perry J.; Levy, Angela D.; Rohrmann, Charles A.; Kende, Amir I.

doi:10.1148/radiol.2243011545

Cited by 117 publications

(57 citation statements)

References 14 publications

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“…Subsequent to diagnosis by histopathological examination, primary neoplasms of the appendix are identified in ~0.5% of all surgically-removed appendices, with carcinoid tumors representing >50% of all appendix neoplasms (2,3). Carcinoid tumors arise from the neuroendocrine cells of the diffuse neuroendocrine system, which are identified in numerous locations, including the lung (25.1%), ovaries (0.5%), biliary system (0.2%) and throughout the gastrointestinal tract (73.4%) (4).…”

Section: Introductionmentioning

confidence: 99%

Carcinoid tumor of the appendix: A case report

Wang

2015

Oncology Letters

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Abstract. Carcinoid tumors are the most common neoplasm of the appendix. The clinical presentation of these lesions is often similar to that of acute appendicitis, or the tumors are asymptomatic. The carcinoids are commonly found incidentally during histopathological examination of the resected appendix following appendectomy or other abdominal procedures. Appendiceal carcinoids usually behave as benign tumors and appendicectomy alone is a sufficient treatment in the majority of cases, while for larger lesions, right colectomy should be performed. The prognosis of patients with local appendiceal carcinoids is excellent. The present study reports the case of a 22-year-old female patient that presented with recurrent right lower abdominal pain of a three-year duration. The patient underwent successful appendectomy and recovered four days later. Subsequently, an appendiceal carcinoid tumor located at the tip of the appendix was diagnosed by histopathological examination. Follow-up examination one year after surgery revealed that the patient was well with no discomfort.

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Section: Introductionmentioning

confidence: 99%

Carcinoid tumor of the appendix: A case report

Wang

2015

Oncology Letters

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“…9,[16][17][18] CT can be used to discover the signs specific to mucocele with high accuracy: appendix lumen more than 1.3 cm, its cystic dilatation, and wall calcification. 3,8,14,16,19,20 By colonoscopy an elevation of the appendiceal orifice is seen and a yellowish mucous discharge would be visible from this orifice. Furthermore, synchronous and metachronous tumors of colon can be identified.…”

Section: Discussionmentioning

confidence: 99%

Mucocele of the appendix: a rare case report

Sudarshan

Reshma

2017

Int Surg J

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Appendiceal mucocele is a rare disease. Sometimes it is discovered accidentally and sometimes it resembles acute appendicitis. Correct diagnosis before surgery is important for the selection of adequate surgical treatment to avoid intraoperative and postoperative complications. Ultrasonography, and particularly computed tomography, should be used extensively for this purpose. If mucocele is treated incorrectly, pseudomyxoma peritonei may develop. We present a case of 22 year old man who was admitted to the emergency department with the signs of acute appendicitis. Emergency open appendectomy was performed. At the time of surgery, a cystic mass was found at the tip of the inflammed appendix. No free fluid was found in the peritoneal cavity. Diagnosis of Mucocele of appendix was suspected. Appendectomy was done and specimen sent for histopathological examination. No lymphadenopathy. Histopathologic diagnosis was subacute appendicitis, mucocele of appendix with simple mucous cyst. Patient is on regular follow-up.

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“…CT can be used to discover the signs specific to mucocele with high accuracy: appendix lumen more than 1.3 cm, its cystic dilatation, and wall calcification. 3,7,9,17,19,22 By colonoscopy an elevation of the appendiceal orifice is seen and a yellowish mucous discharge would be visible from this orifice. Furthermore, synchronous and metachronous tumors of colon can be identified.…”

Section: Discussionmentioning

confidence: 99%

“…3,[7][8][9] It is important to differentiate between these two pathologies before surgery and select adequate surgical tactics. If treated improperly, the mucocele may progress, epithelial cells may escape into the peritoneal cavity, and pseudoyxoma peritonei may develop, which has a high mortality.…”

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confidence: 99%

Mucocele of the Appendix: Case Report and Review of Literature

Demetrashvili

Chkhaidze

Khutsishvili

et al. 2012

International Surgery

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Appendiceal mucocele is a rare disease. Sometimes it is discovered accidentally and sometimes it resembles acute appendicitis. Correct diagnosis before surgery is very important for the selection of adequate surgical treatment to avoid intraoperative and postoperative complications. Ultrasonography, and particularly computed tomography, should be used extensively for this purpose. If mucocele is treated incorrectly pseudomyxoma peritonei, which is characterized by malignant process, may develop. We present a case of a 54-year-old man who was admitted to the emergency department with the signs of acute appendicitis. Open surgery was performed. At the time of surgery, a cystic mass of the appendix with dimensions 7 3 4 33 cm, with inflamed walls, but without perforation was discovered in the right iliac fossa. No discharge was found in the peritoneal cavity. Diagnosis of mucocele was suspected. Only appendectomy was performed because no pathologic process was found in the base of the appendix and lymph nodes were not increased in size. Hystopathologic diagnosis was mucinous cystadenoma. After 2 years, the patient is feeling well.

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Primary Neoplasms of the Appendix Manifesting as Acute Appendicitis: CT Findings with Pathologic Comparison

Abstract: CT findings strongly suggest the presence of underlying neoplasm in the majority of patients with secondary appendicitis.

Cited by 117 publications

References 14 publications

Carcinoid tumor of the appendix: A case report

Carcinoid tumor of the appendix: A case report

Mucocele of the appendix: a rare case report

Mucocele of the Appendix: Case Report and Review of Literature

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