Carcinoid tumor of the appendix: A case report

Gu, Yuqing; Wang, Naichao; Xu, Hongqi

doi:10.3892/ol.2015.2997

Cited by 17 publications

(26 citation statements)

References 14 publications

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“…Histopathology is a best practice because it allows identifying malignancy in up to 1% of patients, most often in the form of neuroendocrine tumor, adenocarcinoma or mucinous cystadenoma 11 . In our study, there was no case of neuroendocrine tumor, despite this being considered the most common appendix primary neoplasm, accounting for approximately 32-57% of tumors of the organ 12 . Adenocarcinoma was the most prevalent tumor in our series; this cancer is rare, accounting for less than 0.5% of all gastrointestinal tumors and between 4-6% of tumors of the appendix.…”

Section: Discussioncontrasting

confidence: 49%

Clinical-epidemiological profile of acute appendicitis: retrospective analysis of 638 cases

Lima¹,

Vieira²,

Oliveira³

et al. 2016

Rev. Col. Bras. Cir.

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Section: Discussioncontrasting

confidence: 49%

Clinical-epidemiological profile of acute appendicitis: retrospective analysis of 638 cases

Lima¹,

Vieira²,

Oliveira³

et al. 2016

Rev. Col. Bras. Cir.

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“…NET comprises the most common neoplasm of the appendix [2]. Nevertheless, NET are rare neuroendocrine neoplasms that are encountered incidentally in 1 out of 200–300 appendectomies [3].…”

Section: Introductionmentioning

confidence: 99%

Frequency, characteristics and outcomes of appendicular neuroendocrine tumors: A cross-sectional study from an academic tertiary care hospital

Abdelaal

Ansari

Al‐Bozom

et al. 2017

Annals of Medicine &Amp; Surgery

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BackgroundAppendicular neuroendocrine tumors (NET, Carcinoid tumors) of the appendix are rare and mostly diagnosed incidentally on the post-operative histopathological examination. NET are usually associated with good 5-year survival rates. We aimed to assess our experience for the diagnosis and management of NET over 11 years.MethodIt is a retrospective chart review of all clinically suspected patients with acute appendicitis who underwent emergent appendectomy with intention to treat between January 2004–December 2014, and were clinically followed up until 2016.ResultsDuring the study period, a total of 13641 patients underwent emergency appendectomy, of which 32 were histologically confirmed NET. The mean age of the NET cases was 25.3 ± 7.9 years; 78% were males and all were clinically presented with acute appendicitis. The mean leucocyte was 15 ± 14 × 109 per Liter, and mean tumor size was 4.86 ± 3.18 (ranged 1.5–13) mm. The median length of hospital stay was 4 (2–15) days. One patient had right hemicolectomy; diagnosed with right colonic cancer with NET being an incidental finding as part of histopathological assessment. Another patient required a second stage procedure; he was diagnosed as goblet cell carcinoid with positive margin. None of the patients died 30-day postoperatively and all of them survived on clinical follow-up that ranged between 2 and 13 years.ConclusionCarcinoid tumors of the appendix are rare and typically diagnosed incidentally. Detailed examination of routine appendectomy specimens is the key for diagnosis. Simple appendectomy suffices for tumors <2 cm for adequate clearance. Appendicular carcinoid tumors are associated with good long-term outcomes.

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“…No obstante, la gran mayoría de casos en los cuales se detecta esta neoplasia suelen ser hallazgos ocasionales secundario a apendicectomías profilácticas en procedimientos quirúrgicos de otra índole, como es el caso de la paciente presentada (6,11).…”

Section: Discussionunclassified

Tumor carcinoide del apéndice cecal: cuando un hallazgo incidental modifica drásticamente el pronóstico y tratamiento del paciente

Rivera

Buitrago-Toro

Gonzales³

2017

Rev. Colomb. Gastroenterol.

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Introducción: la apendicectomía es un procedimiento ampliamente utilizado en todo el mundo, bien sea como consecuencia de signos y síntomas sugestivos de apendicitis aguda o como resección profiláctica.El estudio de la pieza quirúrgica es frecuente, a pesar de la baja incidencia de hallazgos inusuales en esta. Los tumores del apéndice cecal constituyen el 1% de todas las neoplasias intestinales, siendo los de tipo carcinoide los más frecuentes en el apéndice cecal.Objetivo: exponer el caso de un tumor carcinoide del apéndice cecal como hallazgo incidental por apendicectomía profiláctica laparoscópica en un procedimiento ginecológico.Caso clínico: paciente de 58 años de edad, con antecedente patológico de miomatosis uterina e histerectomía en 2010, que consulta por cuadro clínico de dos años de evolución de dolor pélvico crónico. Es llevada a liberación de adherencias intraperitoneales que afectan el apéndice cecal, por lo que se realiza apendicetomía, que en el análisis histopatológico identifica tumor carcinoide típico.Discusión:los tumores carcinoides son neoplasias neuroendocrinas que pueden ser identificadas en múltiples localizaciones; sin embargo, el tracto gastrointestinal es el más frecuente. El compromiso de apéndice cecal no es común y suele ser detectado incidentalmente durante apendicectomías profilácticas. La identificación de este tipo de neoplasias en un estudio de rutina modificará drásticamente el manejo del paciente, ya que dependiendo de su tamaño, extensión y localización, requerirá un manejo y seguimiento específico.

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Carcinoid tumor of the appendix: A case report

Cited by 17 publications

References 14 publications

Clinical-epidemiological profile of acute appendicitis: retrospective analysis of 638 cases

Clinical-epidemiological profile of acute appendicitis: retrospective analysis of 638 cases

Frequency, characteristics and outcomes of appendicular neuroendocrine tumors: A cross-sectional study from an academic tertiary care hospital

Tumor carcinoide del apéndice cecal: cuando un hallazgo incidental modifica drásticamente el pronóstico y tratamiento del paciente

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