Primary melanoma of the gallbladder

Raffensperger, Edward C.; Brason, F. Wells; Treano, Gene

doi:10.1007/bf02237710

Cited by 31 publications

(5 citation statements)

References 5 publications

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“…2,31 Several modalities have been employed in assessing tumors of the gallbladder, including ultrasound, oral cholecystography, intravenous cholangiography, endoscopic retrograde cholangiography, and computed tomography. 6,24,[32][33][34][37][38][39][40][41][42][43] In our study, CT scans uncovered metastatic lesions within the gallbladder in three asymptomatic patients during staging workup, with complete tumor extirpation possible in one case. In patients with widespread metastases, CT scanning was invaluable in assessing tumor burden.…”

Section: 1% Of Cases (4 Of 19) With Primary Lesions and Inmentioning

confidence: 71%

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Melanoma of the gallbladder

Dong

DeMatos

Prieto

et al. 1999

Cancer

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Section: 1% Of Cases (4 Of 19) With Primary Lesions and Inmentioning

confidence: 71%

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] As is true for other mucosal melanomas, most of these patients are in their fourth or fifth decade of life at the time of diagnosis. 17 The mainstay of therapy is surgical excision, with no clear role for adjuvant modalities at this time.…”

mentioning

confidence: 99%

Melanoma of the gallbladder

Dong

DeMatos

Prieto

et al. 1999

Cancer

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“…Involvement of the gallbladder wall is more variable with only mucosal [12,14,26,79,86], submucosal [3], muscularis propria [20,54,80,83,89,109,111], subserosal [45,69,71,91], and serosal [28] involvement all been described. It seems that the presence of necrosis is described more often than in primary lesions [6,20,24,71,79,106,111]. Moreover, there are single reports that mention lymphovascular [46,69,91], and perineural [106] invasion.…”

Section: Morphological Featuresmentioning

confidence: 99%

Melanoma of the gallbladder

2023

Folia Medica Cracoviensia

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Melanoma is a highly malignant neoplasm with the most typical primary locations in the skin and eyeball and rarely reported in the other organs, including the gallbladder. More commonly metastases of melanoma of various primary sites to the gallbladder are observed. However, generally melanoma of the gallbladder is a rare entity with only 217 cases reported in the literature up to date. The paper summarizes knowledge on epidemiology, symptoms, laboratory and imaging findings, morphology, treatment options, and outcome of patients with both primary and metastatic melanoma to the gallbladder.

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“…Cases of associated jaundice and biliary fistulae have also been reported [15,30]. Several modalities have been employed to assess tumors of the gallbladder, including US, CT, MRI [12,14,19,31,[36][37][38][39][40][41]. CT currently represents the first choice and the most widely used method for the staging, surveillance and assessment of therapeutic response in melanoma patients.…”

Section: Melanomamentioning

confidence: 99%

Imaging of gallbladder metastasis

et al. 2021

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Gallbladder metastasis (GM) is a rare condition, often with a late diagnosis or detected upon autopsy. There is no extensive literature on the imaging diagnosis of GM. Here we present a comprehensive review of the literature with the aim of helping to interpret the clinical findings and imaging features of such patients. Few studies on GM are reported in literature. GM by melanoma accounts for about 55.6% of cases. The remaining cases origin from breast cancer (13.6%), hepatocellular carcinoma (13.6%), renal cell carcinoma (6.8%), lung cancer (4.5%), lymphoma (3.5%) and gastric cancer (2.4%). The most common clinical presentation of GM is abdominal pain from cholecystitis due to obstruction of the cystic duct. The main ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) findings that clinicians and radiologists should consider in their everyday medical activity were discussed. The diagnosis of GM was often achieved through a combination of more than one imaging modality. In more than 90% of cases, the diagnosis of GM is often late and combined with other organs involvement in the terminal stage of the malignancy. The knowledge of the clinical features and different imaging techniques through careful evaluation of the gallbladder can help to achieve early diagnosis and avoid misdiagnosis or false negative results.

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Primary melanoma of the gallbladder

Cited by 31 publications

References 5 publications

Melanoma of the gallbladder

Melanoma of the gallbladder

Melanoma of the gallbladder

Imaging of gallbladder metastasis

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