Primary mediastinal liposarcoma: a case report

Abstract

IntroductionLiposarcoma is the most commonly diagnosed soft tissue sarcoma in adults and occurs predominantly in the lower limbs and retroperitoneum. Primary mediastinal liposarcomas are rare.They are often asymptomatic and when growing to large size the presenting symptoms are related to direct invasion or compression of other thoracic organs such as the heart, great vessels and lung.Case presentationA case of a 68-year-old man with primary mediastinal liposarcoma involving the diaphragm and pericardium and successfully managed by complete surgical excision is presented. The patient's postoperative course was uneventful with no evidence of recurrence 9 months after the operation.ConclusionSurgical removal is the optimal treatment for a mediastinal liposarcoma. If the entire tumor can not be resected, surgical debulking often results in symptomatic relief. International literature has demonstrated that recurrent disease occurs and therefore a long-term careful follow up is required.

Surgical management of mediastinal liposarcoma extending from hypopharynx to carina: Case report

“…Warranting further study, radiology and chemotherapy alone seem to be insufficient forms of treatment but are possibly effective as induction or adjuvant therapies [1,2,5]. When determining if surgical intervention is feasible, radiographic films, given the complex anatomy of the mediastinum, can be daunting.…”

Successful Resection of a Large Incidentally Found Primary Mediastinal Liposarcoma

“…However, differentiation from other tumors (including thymoma) arising from the mediastinum remains difficult. The consistency of the tumor can vary from a major fatty aspect to a solid mass (5,6). In the present case, the most probable preoperative diagnosis was a thymoma.…”

Mediastinal Neuro-Fibro-Lipoma with Atypia: A Case Report

“…Mediastinal malignant lipomatous tumors are very rare [1], [3]. They occur in adults around 5th to 6th decades.…”

“…Radiographs are often not very conclusive. Contrast enhanced CT scan is the imaging investigation of choice which reveals low attenuating masses with HU values from −50 to −150 [1]. Soft tissue component may be present with variable attenuation which shows enhancement following IV contrast.…”

“…Mediastinal malignant lipomatous tumors (including primary mediastinal liposaromas and those of the pericardium) are very rare which occur in adults around 5th to 6th decade [1]- [3]. They are usually liposaromas.…”