Primary malignant melanoma of the vagina: A clinicopathological analysis of 10 cases

Pelvic Exenteration for Malignant Melanomas of the Vagina or Urethra with over 3 mm of Invasion

“…Although treatment failures with primary exenteration have been reported [15,17], we believe that 32% local recurrence rate following radical vulvectomy. They suggested that radical surgery should be employed in our three patients with good survival justify a reconsideration of pelvic exenteration as primary treatment for deeply invathe treatment of lesions invading greater than 0.75 mm because of the high local recurrence rate.…”

Vaginal Malignant Melanoma in Treated Patient of Carcinoma Cervix- An Unusual Clinicalentity.

“…VMM accounts for less than 3% of all vaginal malignancies [1] .They occur mostly in post-menopausal women in their fifth and sixth decades and commonly present with vaginal bleeding and discharge or with lump in the lower third of vagina or its anterior wall .Macroscopically, VMM are mostly polypoid and ulcerated with a pigmented appearance [3,5] . The non-pigmented ones look like epithelial tumors of the vagina [3,5] .The most common histopathological variants of VMM are epitheloid (55%), mixed (28%) and spindle (17%) [3,5] .…”

“…The non-pigmented ones look like epithelial tumors of the vagina [3,5] .The most common histopathological variants of VMM are epitheloid (55%), mixed (28%) and spindle (17%) [3,5] . In our case, the tumor was ulcerated with a pigmented appearance, located in upper two-thirds of vagina and pathologically it belonged to the mixed variant.…”

Primary Melanoma of the Vagina Treated by Imatinib: Case Report

“…This extremely rare entity is primarily a disease of postmenopausal women. It accounts for less than 1% of all malignant melanomas, and less than 3% of all primary malignant tumors of the vagina [1].…”