Primary lymphoma arising in the nasal cavity among Japanese

Abstract

Our present study indicates that primary lymphomas arising in the nasal cavity are mostly of NK cell derivation. Our present study also suggests that a small number of cases are derived from NKT-cells.

Extramedullary Plasmacytoma of the Paranasal Sinuses: Combining Surgery with External Radiotherapy

“…Soft tissue plasmacytoma has a significant sex-related susceptibility, with a mean male/ female ratio of 2.7. In this study males were more frequently affected, consistent with data previously reported [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15].…”

“…It accounts for 1 % of all head and neck malignant tumors. The most common sites of EMPs are the nose, paranasal sinuses, nasopharynx and tonsils, but it can also occur in the gastro-intestinal tract, CNS, urinary bladder, thyroid, testes, parotid gland and lymph nodes [3][4][5][6]. Men are more commonly affected, with a median age at diagnosis of 50-60 years.…”

Clinical differences between nasal and extranasal natural killer/T-cell lymphoma: a study of 136 cases from the International Peripheral T-Cell Lymphoma Project

“…6,7,10,13 This may be due to the exclusion of some less bulky nasal cases with limited diagnostic samples from our study. Referral bias is also important since nasal and cutaneous disease may be referred initially to otolaryngology or dermatology centers, 21,22 and the diagnostic material may not be kept after review at the tertiary oncology center. This may also explain the lower incidence of extranasal disease in Japan, which is discordant with previous retrospective series.…”

Ocular involvement in nasal natural killer T-cell lymphoma

“…Nasal NKTL is more frequent in Asia and Central America, and is relatively rare in the US and Europe [13]. Lymphomas arising primarily in the nasal cavity are mostly of T-cell origin and those in the paranasal sinus are more of B-cell origin [14]. Primary nasal lymphomas are mostly of NK cell origin.…”