Primary low‐grade B‐cell lymphoma of the mucosa‐associated lymphoid tissue of the gallbladder

Rajesh, L. S.; Nada, Ritambhra; Yadav, Thakur Deen; Joshi, K.

doi:10.1046/j.1365-2559.2003.01655.x

Cited by 16 publications

(10 citation statements)

References 4 publications

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“…The most common clinical symptom in human patients with gallbladder lymphoma is upper abdominal pain [1, 3, 5,6,7,8, 10, 11, 14,15,16, 18]. One of 2 cats with gallbladder lymphoma also showed a pain response with palpation of the cranial abdomen [7].…”

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confidence: 99%

“…In the dog of this report, we could not elicit upper abdominal pain, suggesting it may be difficult to identify upper abdominal pain in animals with gallbladder lymphoma. Most human patients had cholecystectomies, and the diagnosis of gallbladder lymphoma was histologically confirmed [6,7,8, 10, 11, 13,14,15,16, 18, 19]. Canine gallbladder lymphoma is extremely rare and difficult to diagnose on the basis of symptoms, ultrasonography or hematology and biochemical results, but based on the findings in human medicine, gallbladder lymphoma should be a differential diagnosis for biliary tract obstruction in dogs.…”

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confidence: 99%

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Gallbladder lymphoma in a miniature dachshund

Nagata

Shibata

Sakai

et al. 2015

The Journal of Veterinary Medical Science

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A 7-year-old, miniature dachshund was referred for examination and treatment of persistent anorexia, deep yellow-coloured urine and leucocytosis. The clinical sign of jaundice, results from a serum biochemistry profile and ultrasonographic images suggested a biliary tract obstruction. A cholecystectomy was performed to remove the obstruction. Histopathological assessment of the resected gallbladder and partial common bile duct indicated diffuse large B-cell lymphoma. Twelve days after the initial operation, a second procedure was performed due to bile leakage into the abdominal cavity. Chemotherapy was administered twice after the second operation but discontinued, because the dog showed adverse effects. The dog is still alive 24 months after the surgery. To the authors’ knowledge, this is the first description of canine gallbladder lymphoma.

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confidence: 99%

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confidence: 99%

Gallbladder lymphoma in a miniature dachshund

Nagata

Shibata

Sakai

et al. 2015

The Journal of Veterinary Medical Science

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“…Before the current report, only 9 cases of MALT lymphoma primarily involving the gallbladder and fulfilling confident diagnostic criteria have been described in the literature (Table 1) [5][6][7][8][9][10][11][12][13]. Overall, MALT lymphomas of the gallbladder appear to occur predominantly in elderly women (median age, 69.5 years; male to female, 1-4).…”

Section: Discussionmentioning

confidence: 97%

“…Of the few cases reported in the literature, none has been documented at the genetic level [5][6][7][8][9][10][11][12][13]. Here, we report a case of primary MALT lymphoma of the gallbladder with evidence of API2/MALT1 gene fusion, indicative of a t(11;18)(q21;q21) translocation.…”

Section: Introductionmentioning

confidence: 91%

Primary mucosa-associated lymphoid tissue lymphoma of the gallbladder: report of a case harboring API2/MALT1 gene fusion

Bisig¹,

Copie‐Bergman²,

Baia³

et al. 2009

Human Pathology

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“…Furthermore, in early stages of the disease, the lesion is confined to the submucosal layer leaving the mucosa intact. This finding is of great importance regarding the differential diagnosis from gallbladder adenocarcinoma [1, 20, 21]. On MRI, gallbladder lymphoma lesions show low signal intensity on fat-suppressed T 1 -weighted sequences and high signal intensity on fat-suppressed T 2 -weighted sequences compared with those of liver parenchyma.…”

Section: Discussionmentioning

confidence: 99%

Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding

Psarras

Symeonidis

Vlachaki

et al. 2014

Case Reports in Hematology

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Introduction. Primary lymphoma of the gallbladder is an extremely rare entity with approximately 50 cases reported so far. In many of these cases the presenting symptoms were mimicking symptomatic gallstone disease and the diagnosis was made postoperatively, especially when the preoperative imaging results were far from suspicious for malignant disease. Patients and Methods. We report a case of primary lymphoma of the gallbladder in an 85-year-old man with gallstone disease, who was admitted for elective cholecystectomy 2 months after an episode of acute cholecystitis and pancreatitis. Histological evaluation of the specimen revealed a small lymphocytic lymphoma of the gallbladder. This type of primary gallbladder lymphoma has not been previously reported. Discussion. The most common primary lymphomas of the gallbladder are MALT lymphomas and diffuse large B-cell lymphomas, although a variety of other histological types have been reported. The association of these lesions with chronic inflammation is the most convincing theory for their pathogenesis. For lesions confined to the gallbladder, cholecystectomy is considered to be sufficient, while supplementary chemotherapy significantly improves prognosis in more advanced disease.

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Primary low‐grade B‐cell lymphoma of the mucosa‐associated lymphoid tissue of the gallbladder

Cited by 16 publications

References 4 publications

Gallbladder lymphoma in a miniature dachshund

Gallbladder lymphoma in a miniature dachshund

Primary mucosa-associated lymphoid tissue lymphoma of the gallbladder: report of a case harboring API2/MALT1 gene fusion

Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding

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