Primary liposarcoma of the mastoid

Agarwal, P. N.; Mishra, Swati; Pratap, Vijai

doi:10.1017/s0022215100081408

Cited by 17 publications

(8 citation statements)

References 6 publications

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“…The first adipose tissue mass of the middle ear de scribed in the literature was a liposarcoma causing coalescent mastoiditis, subperiosteal abscess, and a facial palsy in a 4-year-old boy. 10 Other sarcomas of the mid dle ear and mastoid have been well described in the literature, including rhabdomyosarcomas, embryonal cell sarcomas, chondrosarcomas, osteogenic sarcomas and melanomas, lymphomas, plasmacytomas, and eo sinophilic granulomas.' 0 Liposarcomas, however, are usually found in the lower extremities and the retroperitoneum and rarely occur in children."…”

Section: Otolaryngology-mentioning

confidence: 99%

Lipoma of the middle ear: An unusual presentation in a 4‐year‐old child

Selesnick

Edelstein

Parisier

1990

Otolaryngol.--head neck surg.

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Section: Otolaryngology-mentioning

confidence: 99%

Lipoma of the middle ear: An unusual presentation in a 4‐year‐old child

Selesnick

Edelstein

Parisier

1990

Otolaryngol.--head neck surg.

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“…They account for 10 to 15% of soft-tissue sarcomas. 5 Primary liposarcomas of the bone, arising from lipoblasts in the fatty bone marrow, are extremely rare and constitute <0.1% of primary bone tumours, 6 with a wide anatomic distribution (including the femur, [7][8][9][10][11][12][13] humerus, 3,14-17 tibia, 6,18-20 fibula, 21,22 ulna, 23 spine, 24,25 ilium, 10 scapula, 26 and skull [27][28][29] ). Less than 35 cases have been reported, 9 and only 20 of these fulfilled the criteria for primary liposarcoma of bone, 2 and only 16 had definitive photomicrographs.…”

Section: Discussionmentioning

confidence: 99%

Primary Intra-Osseous Liposarcoma of the Femur: A Case Report

Macmull¹,

Atkinson²,

Saso³

et al. 2009

J Orthop Surg (Hong Kong)

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We report a rare case of an intra-osseous liposarcoma of the proximal femur. A 26-year-old man presented with a 6-month history of left groin pain radiating to the knee and an antalgic gait. Radiology showed a predominantly fatty lesion in the medial aspect of the femoral neck extending toward the lesser trochanter; most of the marrow in the femoral neck had been replaced without evidence of an extra-osseous mass; and the posterior cortex had been destroyed. Histological and immunohistochemical analyses of the tumour after open biopsy were indicative of highgrade liposarcomatous malignancy. After exclusion of any other primary tumour foci or metastases on regional and whole-body magnetic resonance images, the diagnosis of a high-grade intra-osseous primary liposarcoma of the proximal femur was made. The patient received 2 preoperative courses of neoadjuvant doxorubicin, cisplatin and methotrexate. After proximal femoral replacement following en bloc excision of the proximal femur, 4 more cycles of adjuvant ifosfamide and etoposide were given. At the 16-month follow-up, he remained independently ambulatory, with no local or distant recurrence. Tissue diagnosis and multimodal imaging, rather than any single radiological investigation, are important in making the diagnosis.

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“…None of the previously reported cases of middle-ear lipoma has been associated with facial palsy. Agarwal et al , 7 however, described a case of unilateral facial nerve palsy caused by a primary liposarcoma in a four-year-old boy.…”

Section: Discussionmentioning

confidence: 99%