Primary leiomyosarcoma of the thyroid

Ege, Bahadır; Leventoğlu, Sezai

doi:10.4174/jkss.2013.85.1.43

Cited by 11 publications

(11 citation statements)

References 8 publications

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“…Thyroid leiomyosarcoma is a mesenchymal malignant tumour with smooth muscle differentiation, arising from the smooth muscle cells of the vessels located in the thyroid capsule (2). Instead of metastasizing to regional lymph nodes (7,9), leiomyosarcoma appears to invade adjacent tissue.Thus radical surgery is essential (7,8,9,11,12,14). Previous studies have shown that, in patients with a large or locally aggressive tumour, the more aggressive the procedure, the more beneficial it is (13,14).…”

Section: Discussionmentioning

confidence: 99%

“…Sarcomas are thought to originate from the wall of blood vessels [1]. The etiology of primary thyroid leiomyosarcomas remains unclear, however, certain authors have postulated that it may originate from the smooth muscle in the vascular walls (7,10,(11)(12)(13). They account for 6% of the head and neck tumours, of which only 0.014% of Leiomyosarcomas cases develop in the thyroid gland (7,8,9,10,13,14), with an estimated 1year survival rate of 5-10% (10,12).Primary thyroid leiomyosarcomais an extremely rare soft tissue cancer.…”

Section: Introductionmentioning

confidence: 99%

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Leiomyosarcoma : Case Report of a Rare Primary Smooth Muscle Tumour of the Thyroid Gland

Kothari¹,

Godkhindi²,

Shetty³

et al. 2017

Journal of Health and Allied Sciences NU

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Primary smooth muscle tumours of the thyroid gland are extremely rare neoplasms. There are concerns regarding the management of such disease due to its rarity. Around 22 cases have been reported in the literature till date. In this study, the case of a 63year old female patient who presented with a rapidly enlarging anterior neck mass over the period of 3 months is reported. The patient underwent thyroidectomy with tracheostomy and radiotherapy for the treatment of primary leiomyosarcoma of thyroid gland. Due to similar clinical presentation as anaplastic carcinoma, diagnosis of primary thyroid leiomyosarcomas is difficult and maybe misdiagnosed. Hence the combined assessment of clinical, imaging and pathological data is required.Immunohistochemical analysis is a gold standard for diagnosis. Diagnosis and treatment of the current patient with primary thyroid leiomyosarcomaand a comprehensive review of the relevant literature are presented herein

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Leiomyosarcoma : Case Report of a Rare Primary Smooth Muscle Tumour of the Thyroid Gland

Kothari¹,

Godkhindi²,

Shetty³

et al. 2017

Journal of Health and Allied Sciences NU

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“…The etiology of primary thyroid LMS remains unclear, however, certain authors have postulated that it may originate from the smooth muscle in the vascular walls ( 6 , 10 , 14 , 16 – 18 ). In addition, LMS appears to invade adjacent tissue rather than metastasizing to regional lymph nodes ( 6 , 11 ), thus, radical surgery is essential ( 6 , 10 , 11 , 16 , 17 , 19 ). The complexity of the procedure depends on tumor size and adjacent tissue/organ involvement.…”

Section: Discussionmentioning

confidence: 99%

“…Primary thyroid leiomyosarcoma (LMS) is an extremely rare soft tissue cancer, with only 22 reported cases to date ( 1 – 19 ). LMS is commonly observed in the gastrointestinal tract, retroperitoneum and pelvis ( 10 , 16 ); however, only 0.014% of LMS cases develop in the thyroid gland ( 6 , 10 , 11 , 13 , 18 , 19 ), with an estimated 1-year survival rate of 5–10% ( 13 , 17 ). Primary thyroid LMS most commonly occurs in the elderly with a predilection for female patients, and typically presents as a painless, rapidly growing neck mass.…”

Section: Introductionmentioning

confidence: 99%

Primary thyroid leiomyosarcoma: A case report and literature review

Zou

Ning

et al. 2016

Oncology Letters

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Primary thyroid leiomyosarcoma (LMS) is an extremely rare soft tissue cancer; only 22 cases have been reported in the literature to date. In the current study, the case of an 83-year-old male patient who presented with a neck mass that had grown rapidly over the previous 3 months is reported. The patient underwent thyroid lobectomy twice and two cycles of immunotherapy for the treatment of primary thyroid LMS; however, he succumbed to the disease 5 months after the second surgery. An accurate diagnosis of primary thyroid LMS is difficult, as the disease is often misdiagnosed as anaplastic carcinoma, and requires the combined assessment of clinical, imaging and pathological data. Diagnosis of the current patient with primary thyroid LMS and a comprehensive review of the relevant literature are presented herein.

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“…Primary LMS of the thyroid is a rare tumour and approximately only 30 cases have been reported previously. [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] The other common sites for LMS are gastrointestinal tract, retroperitoneum and pelvis. 23 According to the histological tumour classification by World Health Organization (WHO), thyroid LMS is classified as a member of the smooth-muscle tumours of thyroid gland.…”

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confidence: 99%