Primary Leiomyosarcoma of the Kidney

Saini, Monika; Niveditha, S R; Krishnagiri, Chaithra; Babu, Sudarshan

doi:10.4061/2010/652398

Cited by 29 publications

(39 citation statements)

References 7 publications

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“…The most common site of metastasis is the lungs. The liver and lymph nodes are the second most common site of metastasis [1]. Low-grade sarcomas frequently cause local recurrences and surgical removal of the recurrence extends the survival.…”

Section: Discussionmentioning

confidence: 99%

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High-Grade Primary Leiomyosarcoma of the Kidney

Ozturk

2014

World J Nephrol Urol

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Leiomyosarcomas account for 0.8 to 2.7% of all malignant renal tumors. Like the leiomyomas, the leiomyosarcomas originate from the cells of the renal capsule, pelvis renalis, the calyces and smooth muscle of the blood vessels. They are two-folds more common in women and most frequently seen in the fourth and sixth decades. They are solitary lesions. Their major symptoms are pain, palpable mass and hematuria. Clinical, radiological and pathological findings of a 51 years old patient presenting with diagnosed flank pain and nausea and diagnosed as having high-grade primary renal leiomyosarcomas were evaluated under the light of current literature.

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Section: Discussionmentioning

confidence: 99%

“…Renal leiomyosarcoma may originate from the renal pelvis, calyces, renal capsule and renal vessels but their most common site of origin is smooth muscle of the renal veins [1]. Fifty to sixty per cent of the renal sarcomas are leiomyosarcoma.…”

Section: Introductionmentioning

confidence: 99%

High-Grade Primary Leiomyosarcoma of the Kidney

Ozturk

2014

World J Nephrol Urol

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“…Leiomyosarcoma account for 50-60% of kidney sarcomas; followed by liposarcomas in 10-15% of cases 1 . They usually occur in the right kidney 2 .…”

Section: Introductionmentioning

confidence: 99%

Primary Renal Leiomyosarcoma: A Case Report

Singh¹

2018

jmscr

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“…3 Leiomyosarcomas (LMS) originate from the smooth muscles of the renal capsule, renal pelvis, calyxes, and blood vessels, last one is the most frequent. 4,5 Overall, primary renal sarcomas show a female predilection and present in the age ranging from 28 to 70 years, with a median age of 49 years.…”

Section: Introductionmentioning

confidence: 99%

Primary renal leiomyosarcoma: a rare entity

Beigh¹,

Bilal²,

Sheikh³

et al. 2018

Int J Res Med Sci

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Background: Primary leiomyosarcoma of the kidney is an exceptionally rare tumor with an aggressive behavior. However, reported literature is very limited. Since the prognosis for a renal sarcoma is extremely poor, differentiation from sarcomatoid renal cell carcinoma (RCC) is necessary. Histopathology and immunohistochemistry are the only modes of diagnosing these sarcomas as they have no specific diagnostic features clinically and radiologically. Objectives was to evaluate the clinicopathological pattern of leiomyosarcomas arising from kidney.Methods: This study was conducted in the Department of Pathology, Government Medical College, Srinagar. It was a retrospective study done over a period of 3 years, July 2014 to June 2017. A total of 4 patients, who underwent surgery and were diagnosed with primary LMS of the kidney, were included in the present study.Results: The study was done to evaluate the clinicopathological pattern of 4 cases of primary renal LMS diagnosed at a tertiary care hospital. Age of the patients ranged from 35-64 years with a mean age of 53.5 years. Sex ratio of 1:1 was observed. Major presenting symptom was flank pain (75%) followed by mass abdomen (50%). Also, one of the patients presented with spontaneous rupture of kidney. Radical nephrectomy was done in all patients. On gross examination tumor had originated from renal pelvis (50%) in 2 patients, renal vein (25%) in one patient whereas, renal capsule (25%) appeared to be the site of origin in other patient. Histopathological examination and immunohistochemistry proved the lesion as primary leiomyosarcoma of kidney.Conclusions: Being a rare tumour, renal leiomyosarcoma needs to be considered in the differential diagnosis of renal masses even in patients younger than 40 years.

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Primary Leiomyosarcoma of the Kidney

Cited by 29 publications

References 7 publications

High-Grade Primary Leiomyosarcoma of the Kidney

High-Grade Primary Leiomyosarcoma of the Kidney

Primary Renal Leiomyosarcoma: A Case Report

Primary renal leiomyosarcoma: a rare entity

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