Primary Intraparenchymal Squamous Cell Carcinoma of the Kidney: A Rare and Unique Entity

Ghosh, Pranab; Kaushik, Sushmita

doi:10.1155/2014/256813

Cited by 21 publications

(32 citation statements)

References 7 publications

(10 reference statements)

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“…Urinary calculi and chronic inflammation are some of the important factors associated with renal squamous cell carcinomas (4,5). In the present case, the patient has a history of kidney calculi for >14 years and surgery was performed to remove the stone.…”

Section: Discussionmentioning

confidence: 78%

“…Primary kidney pelvic squamous cell carcinomas account for 0.5-0.8% in kidney malignancies (1). Renal parenchyma squamous cell carcinomas are extremely rare; to the best of our knowledge only 3 cases have been reported until now (2)(3)(4)(5).…”

Section: Discussionmentioning

confidence: 99%

“…The patient exhibited chronic urinary inflammation and antibiotics were intermittently prescribed. These are two predisposing factors associated with the development of squamous cell carcinomas (4)(5).…”

Section: Discussionmentioning

confidence: 99%

“…Kidney squamous cell carcinomas are rare occurrences in renal malignancies, particularly for kidney parenchyma squamous cell carcinoma (1)(2)(3)(4)(5). To the best of our knowledge, only three cases of patients with kidney parenchyma cell carcinoma have been reported since December 2014 (2-5).…”

Section: Introductionmentioning

confidence: 99%

“…All the patients underwent nephrectomies. The 73-year old man was followed up 3 months after surgery, the 51-year old man was followed up 6 and 12 months after surgery and the 60-year old woman was followed up 13 months after surgery; all patients remained alive with no evidence of disease at the time of follow-up (2)(3)(4)(5). The present study reports a case of kidney parenchyma squamous cell carcinoma with inflammation invasion, which mimicked xanthogranulomatous pyelonephritis on radiological examination; the literature concerning kidney squamous cell carcinomas is also reviewed.…”

Section: Introductionmentioning

confidence: 99%

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Primary kidney parenchyma squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: A case report

et al. 2016

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Abstract. Primary kidney parenchyma squamous cell carcinoma is extremely rare, and this is the forth case to be reported. In the present study, a case of a 61-year old man is discussed. The man presented with recurrent lumbago, gross hematuria for nearly 2 months, and suspicious inflammatory kidney diseases on contrast-enhanced computed tomography (CT) and fludeoxyglucose-positron emission tomography (FDG-PET)/CT, but a tumor can not be excluded completely prior to surgery. Finally, radical nephrectomy was performed, and histological analysis determined that the diagnosis was kidney parenchyma squamous cell carcinoma with inflammation invasion. The present case highlights the potential confusion of preoperative diagnosis of renal tumor with inflammation, and introduces the potential role of FDG-PET in its diagnosis and survival evaluation in renal malignancies.

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Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Primary kidney parenchyma squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: A case report

et al. 2016

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Primary squamous cell carcinoma of the kidney with hepatic invasion

Takanashi,

Asaoka,

Imano

et al. 2024

IJU Case Reports

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IntroductionPrimary squamous cell carcinoma of the kidney is rare, with only a few cases reported to date.Case presentationA right renal mass was detected in a 73‐year‐old asymptomatic man. Dynamic contrast‐enhanced computed tomography showed a hypodensity mass extending from the upper pole of the kidney to the right lobe of the liver. Renal biopsy revealed that this tumor was squamous cell carcinoma. One month later, computed tomography showed rapid tumor growth. Radical nephrectomy and partial hepatic resection were performed. Pathological analysis indicated that this tumor originated from the tubular epithelium, and the patient was diagnosed with primary squamous cell carcinoma of the kidney.Following up without adjuvant therapy, he developed retroperitoneal recurrence and multiple lung metastases and expired.ConclusionIn this case, squamous cell carcinoma of the kidney invaded the liver and progressed rapidly. Considering these observations, surgical resection should be promptly performed in suspected cases.

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Primary squamous cell carcinoma of the kidney parenchyma with ascending colon invasion: A case report and literature review

Kim

2022

International Journal of Surgery Case Reports

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Introduction Primary squamous cell carcinoma (SCC) of the kidney parenchyma is extremely rare, with only seven cases reported to date. Herein, we present a case of primary with colon invasion. Presentation of case A 61-year-old man presented right flank pain for 5 months. Computed tomography (CT) showed multiple renal stones and a necrotic mass in the lower pole of the right kidney, which was suspicious for ascending colon invasion. There was no history of radiation or occupational exposure to chemicals. Radical nephrectomy, right hemicolectomy, and lymph node dissection were performed. The kidneys showed a solid mass with multiple renal stones. The tumor comprised nests of atypical squamous cells and keratin pearls; however, the renal pelvis was normal. 18-Fluorodeoxyglucose-positron emission tomography/CT failed to demonstrate other primary site. Therefore, the patient was diagnosed as primary SCC of the kidney. The patient did not receive adjuvant therapy and was alive during follow-up for 6 months after surgery. Discussion SCC of the urinary tract is considered to be the result of squamous metaplasia of the urothelium, which may potentially progress to SCC. Squamous metaplasia may be caused by chronic irritation. However, the mechanism of SCC remains unclear. Although the prognosis of SCC is similar to that of urothelial carcinoma when compared stage for stage, SCC tends to be diagnosed at a more advanced stage. Conclusion This is a rare case of kidney SCC with adjacent organ invasion. Additional studies are required to further our understanding of this rare tumor and improve diagnosis and treatment.

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Primary Intraparenchymal Squamous Cell Carcinoma of the Kidney: A Rare and Unique Entity

Cited by 21 publications

References 7 publications

Primary kidney parenchyma squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: A case report

Primary kidney parenchyma squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: A case report

Primary squamous cell carcinoma of the kidney with hepatic invasion

Primary squamous cell carcinoma of the kidney parenchyma with ascending colon invasion: A case report and literature review

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