Primary intermediate-grade cardiac myxofibrosarcoma with osseous metaplasia: an extremely rare occurrence with a previously unreported feature

Sánchez-Uribe, Magdalena; Retamero, Juan Antonio; Leon, J Gomez; Perez, Jorge Montoya; Quiñonez, Enoe

doi:10.1016/j.carpath.2014.07.006

Cited by 9 publications

(9 citation statements)

References 10 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of these, 76.5% were benign cardiac tumors, and 23.5% were malignant, and of the malignant tumors, onethird were angiosarcomas, 20% were rhabdomyosarcomas, 15% were mesotheliomas, and 10% were fibrosarcomas. [5][6][7][8][9] Myxofibrosarcomas are most commonly found in the left atrium, but have been reported to arise in all chambers. 11 Primary cardiac myxofibrosarcomas are extremely rare.…”

Section: Discussionmentioning

confidence: 99%

“…To the best of our knowledge, only 22 cases have been reported. [5][6][7][8][9] Myxofibrosarcomas are most commonly found in the left atrium, but have been reported to arise in all chambers. Patients' ages ranged from 6 to 81 years.…”

Section: Discussionmentioning

confidence: 99%

“…3 Fibrosarcoma is a rare cardiac tumor, representing about 5% of AFIP cases and recent series of cardiac sarcomas resected at surgery. [5][6][7][8][9] Here, we present a case of primary cardiac myxofibrosarcoma in which pleural effusion cytology and imprint cytology specimens were obtained at resection and autopsy. [5][6][7][8][9] Here, we present a case of primary cardiac myxofibrosarcoma in which pleural effusion cytology and imprint cytology specimens were obtained at resection and autopsy.…”

mentioning

confidence: 99%

“…4 Myxofibrosarcoma is a variant of fibrosarcoma, and only 22 cases of cardiac myxofibrosarcoma have been reported in the literature. [5][6][7][8][9] Here, we present a case of primary cardiac myxofibrosarcoma in which pleural effusion cytology and imprint cytology specimens were obtained at resection and autopsy. Immunocytochemistry with a cell transfer technique of the pleural fluid and imprint cytology specimens were performed.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Myxofibrosarcoma of the heart: A case report with positive pleural effusion cytology

Hagiwara

Nakamura

Taguchi

et al. 2016

Diagnostic Cytopathology

View full text Add to dashboard Cite

Primary cardiac sarcoma is rare, and there have been only a few reports on its cytologic findings. Myxofibrosarcoma, a variant of fibrosarcoma of the heart, is an extremely rare entity. We present a case of primary cardiac myxofibrosarcoma in a 63-year-old woman. Pleural fluid cytology and imprint cytology of the resected tumor at operation and autopsy were obtained. Cytologic evaluation with immunocytochemical staining utilizing a cell transfer technique revealed that tumor cells of the resected tumor and autopsy specimen and pleural effusion demonstrated large and pleomorphic cells with irregular, hyperchromatic nuclei and were positive for vimentin. Combination of morphology and immunoprofile of the cells of pleural effusion was compatible with the diagnosis of metastatic myxofibrosarcoma. Diagn. Cytopathol. 2016;44:1112-1116. © 2016 Wiley Periodicals, Inc.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Myxofibrosarcoma of the heart: A case report with positive pleural effusion cytology

Hagiwara

Nakamura

Taguchi

et al. 2016

Diagnostic Cytopathology

View full text Add to dashboard Cite

show abstract

“…MFS is most often found on the limbs of aged male people, but extremely uncommon in the liver. Rare occurrences have been reported in cranial cavity [4], orbit [5], maxilla [6], parotid gland [7], hypopharynx [8], sinus piriformis [9], vocal folds [10], thyroid gland [11], esophagus [12], breast [13], heart [14], aorta [15], scapular region [16], buttock [17], and scrotum [18]. By literature review, hepatic MFS has never been reported previously except one metastasis [19].…”

Section: Introductionmentioning

confidence: 99%

Primary low grade myxofibrosarcoma of the liver with benign presentation but malignant outcome: a case report

Shao

Jiao

et al. 2019

BMC Cancer

View full text Add to dashboard Cite

BackgroundMyxofibrosarcoma (MFS) is most often found on the limbs of aged male people, but extremely uncommon in the liver.Case presentationA 52-year-old female patient with a liver mass was diagnosed as a primary MFS. It had no obvious abdominal symptoms, and the tumor was resected with an extended margin. Three years after the surgery, the patient was readmitted for peritoneal metastasis and passed away 4 months later. The tumor has a benign presentation, but malignant outcome.ConclusionsComprehensive radiological inspection, intensive preoperative evaluation, careful design of operating procedures, wide margin resection, consecutive treatment, and strict periodical follow-ups should be taken to ensure a better prognosis of this kind of neoplastic disease.

show abstract

A rare presentation of primary cardiac myxofibrosarcoma: Case report and literature review

Soltani,

Garousi,

Mirzaee

et al. 2024

Cancer Reports

View full text Add to dashboard Cite

BackgroundPrimary cardiac myxofibrosarcoma is a rare and aggressive malignancy, with the majority of approaching strategies relying on case reports. This article provides insights into its diagnosis and treatment.Case PresentationThis paper presents the case of a 40‐year‐old man with sudden onset hemoptysis, leading to the diagnosis of primary cardiac myxofibrosarcoma. Treatment involved open‐heart surgery to excise the left atrium tumor, followed by 6 cycles of adjuvant chemotherapy. Unfortunately, brain metastasis developed, leading to the patient's death 1 year after initial diagnosis.ConclusionPrimary cardiac myxofibrosarcoma remains a clinical challenge with an unfavorable prognosis. Early diagnosis through advanced imaging is crucial, and research is needed to explore innovative treatments. This case underscores the complexities of managing this rare cardiac malignancy and highlights the necessity for ongoing investigations to enhance patient outcomes.

show abstract

Primary intermediate-grade cardiac myxofibrosarcoma with osseous metaplasia: an extremely rare occurrence with a previously unreported feature

Cited by 9 publications

References 10 publications

Myxofibrosarcoma of the heart: A case report with positive pleural effusion cytology

Myxofibrosarcoma of the heart: A case report with positive pleural effusion cytology

Primary low grade myxofibrosarcoma of the liver with benign presentation but malignant outcome: a case report

A rare presentation of primary cardiac myxofibrosarcoma: Case report and literature review

Contact Info

Product

Resources

About