Primary HIV-1 infection: Diagnosis, pathogenesis, and treatment

Abstract

Primary HIV-1 infection represents the time when the virus is first disseminating throughout the body and induces host immune responses. Diagnosing this stage of disease requires an understanding of who is at risk, the clinical manifestations of primary infection, and how the diagnosis is made. Identifying these individuals allows for counseling to prevent further transmission to others and the potential benefits associated with early antiretroviral therapy. Moreover, studying these individuals provides important insight into the biology of HIV-1 transmission and immunopathogenesis.

Low back pain and fever as the first symptoms of AIDS: case report

“…Therefore, it is necessary that health professionals keep a high level of suspicion in all patients with compatible symptoms and who report recent risk behavior. 6,7 The medical literature describes a wide range of clinical manifestations of primary infection, with fever and rash as the main signals. 8 Neurological manifestations as brachial neuritis, peripheral neuropathy, facial palsy, lymphocytic meningitis and encephalopathy were also observed.…”