Primary glioblastoma of the cerebellum in a 19-year-old woman: a case report

Abstract

IntroductionCerebellar glioblastoma is an uncommon adult lesion. The pathogeny and prognosis of cerebellar glioblastoma are still incompletely elucidated.Case presentationWe report the case of a 19-year-old Moroccan woman. A neurologic examination revealed the presence of cerebellar signs. A diagnosis of cerebellar glioblastoma is rarely made before surgery. An encephalic computer tomography scan and magnetic resonance imaging increased the accuracy of defining the nature of the lesion. Magnetic resonance imaging showed a heterogeneously enhancing mass in the vermis and the right cerebellar hemisphere. After surgery, glioblastoma was histologically confirmed. Post-operative radiotherapy followed. The outcome of our patient was favorable after one year of follow-up.ConclusionsWe report an unusual case of cerebellar gliobastoma. Cerebellar glioblastoma multiforme should be considered in the differential diagnosis of a cerebellar mass lesion.

Primary glioblastoma of the cerebellar vermis: A case report

“…The pathology of a lesion can only be confirmed after surgery. Brain metastases always have necrosis within them and show greater than one lesion with marked peripheral edema (1,2,4,9). The history of a primary tumor is important.…”

“…Cerebellar glioblastoma treatment is usually palliative, consisting of surgery, radiotherapy and chemotherapy (1,2). Decisions regarding surgery depend on factors such as patient age, performance, diseased region in the brain and resectability of the tumor (1,2,4,6).…”

“…The best treatment for cerebellar glioblastoma is removal of as much of the tumors as possible but keeping surgical morbidity to a minimum (2). The prognosis of cerebellar glioblastoma is similar to that of anaplasic astrocytoma (1). In the current study, a case of primary cerebellar glioblastoma is presented, and the physiopathology, clinical presentation, diagnosis, differential diagnosis, treatment and general outcome of this disease is discussed.…”

“…Hypertension, impaired balance and gait disturbance are typical clinical manifestations (1). The best treatment for cerebellar glioblastoma is removal of as much of the tumors as possible but keeping surgical morbidity to a minimum (2).…”

Glioblastoma Multiforme Cerebelar

“…A infiltração no parênquima cerebral constitui fator limitante para a ressecção cirúrgica completa, resultando em pior prognóstico 6,7 .…”