Primary falcine chondrosarcoma

Kathiravel, Y.; Finnis, N.D.M.

doi:10.1016/j.jocn.2007.08.005

Cited by 9 publications

(12 citation statements)

References 19 publications

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“…Intracranial chondrosarcomas of dural origin are very rare, and only 53 cases have been reported till date. [1][2][3][4][5][6][7][8][9][10][11][12] Though majority of the skull-base chondrosarcomas are of classic variant (> 80%), dural-based chondrosarcomas are predominantly of mesenchymal variant (60%). Of the 25 falcine and parasagittal chondrosarcomas reported so far, only 12 cases were of classic variant (►Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…Of the 25 falcine and parasagittal chondrosarcomas reported so far, only 12 cases were of classic variant (►Table 1). [1][2][3][4][5][6][7][8][9][10][11][12] The remaining cases were predominantly mesenchymal with only one myxoid variant. There was a strong female preponderance.…”

Section: Discussionmentioning

confidence: 99%

“…There was a strong female preponderance. [1][2][3][4][5][6][7][8][9][10][11][12] In this article, the authors report a case of classic variant of chondrosarcoma that was dural based and parafalcine in location.…”

Section: Discussionmentioning

confidence: 99%

“…On review of the literature, the authors found there were no recurrences for dural-based classic chondrosarcomas after gross resection (the maximum follow-up period noted was 6 years). [1][2][3][4][5][6][7][8][9][10][11][12] High-dose photon and/or proton beam therapy, which both have acceptable side effects, have been used for residual skull base chondrosarcomas and seem to provide superior results to conventional radiation techniques. 13 In this case, the treatment was limited to surgery alone as the tumor exhibited good dissection margins from the surrounding tissue, and hence total resection was achieved.…”

Section: Discussionmentioning

confidence: 99%

“…Since the first description of intracranial chondrosarcoma by Mott in 1899, only 53 cases chondrosarcomas arising above the skull base have been reported and most of these are of the highly malignant mesenchymal variant. [1][2][3][4][5][6][7][8][9][10][11][12] Only 12 cases of classic variant chondrosarcomas have been reported in the falcine/parafalcine location (►Table 1). [2][3][4][5][6][7][8][9][10][11][12] The authors report one more case of classic chondrosarcoma arising in such an unusual location.…”

mentioning

confidence: 99%

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Parafalcine Chondrosarcoma: Unusual Localization for a Classic Variant

Naik

Velho

Guha

2019

IJNS

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Parafalcine Chondrosarcoma: Unusual Localization for a Classic Variant

Naik

Velho

Guha

2019

IJNS

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Osteochondroma of the convexity: pathologic-neuroimaging correlates of a lesion that mimics high-grade meningioma

Somerset

Kleinschmidt-DeMasters

Rubinstein

et al. 2009

J Neurooncol

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Intracranial chondromas are uncommon benign lesions usually attached to dura and located over the convexity of the skull. Osteochondromas are even rarer and additionally contain a benign bony component. Both lesions are reportedly difficult to distinguish from meningiomas on pre-operative neuroimaging studies, although few detailed pathologic-neuroimaging correlation studies have appeared in the literature, particularly for intracranial osteochondromas. A 33-year-old woman with a 4-year history of headaches presented with recent onset of left-sided muscle spasms and weakness. Two days prior to admission to our hospital, neuroimaging studies had shown a large right convexity mass with unusual multifocal bright signal intensities throughout an otherwise isointense mass. The bright signals were interpreted as showing multifocal hemorrhage and the mass was felt to be a convexity meningioma. However, subsequent catheter angiography characterized the lesion as being avascular. The mass was resected en bloc. Extensive histological sectioning revealed a benign osteochondroma predominantly composed of lobules of hypocellular cartilage. Microdissection of the different components revealed that the multifocal, spicule-like bright foci interpreted as hemorrhage on neuroimaging studies were instead foci of benign bone containing metaplastic bone marrow with trilineage hematopoietic cell populations and adipose tissue. Centrally, the hilum of the lesion contained avascular loose connective tissue. No recent or remote hemorrhage was identified anywhere in the lesion. Rare convexity osteochondromas may be mistaken for high-grade meningiomas on neuroimaging studies; their avascular nature, coupled with their complex signal pattern can serve as clues to the correct pre-operative diagnosis.

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