Primary Ewing sarcoma of the vertebral column: Case report and literature review

Lmejjati, M.; Attar, H. El; Layadi, F.; Belaabidia, B.; Ali, S. Ait Ben

doi:10.1055/s-0035-1557395

Cited by 3 publications

(7 citation statements)

References 14 publications

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“…ES occurs in the second decade of life under the age of 30 years, its occurrence after the age of 30 is rare (4,5). They were 03 years and 10 years old boys in our cases.…”

Section: Discussionmentioning

confidence: 53%

“…Ewing's sarcoma is a rare tumor, accounting for 10% of all primary malignant bone tumors in children and 3% of all malignant tumors in childhood (4). Symptoms are dominated by pain which is present in 94-100% and neurological deficit in 50-94% due to spinal cord compression (5)(6)(7)(8), however, it is rarely posted traumatically neglected with intradural and extra-spinal imaging features.…”

Section: Introductionmentioning

confidence: 99%

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Childhood spinal extradural EWING'S sarcoma: A case report

Alngar¹,

Hamdaoui²,

Bankole³

et al. 2022

World J. Adv. Res. Rev.

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Extraosseous, extradural and extramedullary Ewing's sarcoma is a rare tumor that usually affects young people. We report a 10 years old child operated for Inguinal Hernia at the age of 4 years which presents a lumbar spinal syndrome for 4 months, the second is a 3 years old child with a history of falls on stairs 4 months ago, presented for 14 days before his admission a right leg paresis at ⅗ on the muscular testing, associated with fever. Both patients underwent magnetic resonance imaging that showed a compressive extradural process from L2 to L5 for the first case and a compressive extradural process from L4 to S2 for the second case. The patients benefited from macroscopic total resection by laminectomy. Histology confirms the diagnosis of Ewing’s Sarcoma. Both patients were referred at discharge to the pediatric oncology department for complementary chemotherapy management. The long-term follow-up at three years was good clinically with no recurrence on imaging. Spinal Ewing’s Sarcoma extradural without bone involvement remains rare and its overall survival at 5 years is still poor.

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“…ES occurs in the second decade of life under the age of 30 years, its occurrence after the age of 30 is rare (4,5). They were 03 years and 10 years old boys in our cases.…”

Section: Discussionmentioning

confidence: 53%

Section: Introductionmentioning

confidence: 99%

Childhood spinal extradural EWING'S sarcoma: A case report

Alngar¹,

Hamdaoui²,

Bankole³

et al. 2022

World J. Adv. Res. Rev.

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“… 6 Magnetic resonance imaging represents the gold standard for early diagnosis, assessment of the extent of the tumor in the soft tissues and determination of the therapeutic strategy. 10 …”

Section: Discussionmentioning

confidence: 99%

“…In this location, neurogenic tumors, malignant lymphoma, rhabdomyosarcoma, synoviolosarcoma, and Histiocytosis are the representative differential diagnoses; it is difficult to make a definitive diagnosis of Ewing sarcoma. 10 …”

Section: Discussionmentioning

confidence: 99%

“…10 In this location, neurogenic tumors, malignant lymphoma, rhabdomyosarcoma, synoviolosarcoma, and Histiocytosis are the representative differential diagnoses; it is difficult to make a definitive diagnosis of Ewing sarcoma. 10 The diagnosis of Ewing's sarcoma is based on histology, immunophenotyping and the demonstration of one of the specific translocations. The tumor expresses CD99 in 90% of cases.…”

Section: Discussionmentioning

confidence: 99%

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Primary Ewing’s Sarcoma of the Spine: About a Case

Cherraqi

Lemrabet

Diallo

et al. 2022

Global Pediatric Health

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Ewing’s sarcoma is a primary malignant bone tumor affecting individuals in the second decade of life. Primary sarcomas of the spine are rare and the occurrence of primary Ewing’s sarcoma in the spine is very rare. There are 2 types of Ewing’s sarcoma of the spine, Ewing’s sarcoma of the sacral spine which is very aggressive with a poor prognosis and Ewing’s sarcoma of the non-sacral spine which is an extremely rare occurrence. The patient may have a neurological deficit when the tumor extends into the spinal canal, causing compression of the spinal cord. Magnetic resonance imaging (MRI) is very sensitive in diagnosing the tumor and Evaluation of the extent of the tumor. Here, we report the case of a 12-year-old boy who presented with low back pain, weakness of both lower limbs and bilateral spastic paraplegia progressively evolving since 1 month. The CT and MRI scans showed the presence of a tissue lesion process centered on the vertebral body of L1, heterogeneously enhanced after injection of Gadolinium respecting the posterior arch, without bulging of the posterior wall with epiduritis, endocanal extension and spinal cord compression. The patient underwent decompression with surgical biopsy and posterior stabilization of the spine. Histopathology and immunohistochemistry studies confirmed the diagnosis of Ewing’s sarcoma and the patient was referred to an oncopediatric center for combined chemotherapy and radiotherapy, but died at home a few days later before the start of treatment.

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