1976
DOI: 10.1159/000251107
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Primary Eruption of Prurigo simplex subacuta

Abstract: 28 patients with typical picture of prurigo simplex subacuta were examined for the primary eruption. In all patients, the first visible lesion was a papule, at the top of which a vesicular element was never seen. 46 biopsy specimens of the initial eruption were serially sectioned. The histological changes were found in connection with hair follicles, which consisted of spongiosis and mononuclear cell migration at the follicular epidermis and perifollicular infiltrates of mononuclear cells.

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Cited by 28 publications
(16 citation statements)
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“…Our patient presented with typical symptoms and signs of subacute prurigo, a prurigo variant that is characterized by severely pruritic and excoriated papules that are smaller and less elevated than those of prurigo nodularis; however, the histopathologic findings, in particular the dense infiltration of neutrophils with scant eosinophils, were atypical for subacute prurigo, which usually shows spongiosis and a mixed perivascular and/or perifollicular infiltrate with scattered interstitial eosinophils 1,2 . Surprisingly, linear BMZ deposits of IgA and C3 were detected by DIF, and a diagnosis of LAD was made.…”
Section: Discussionmentioning
confidence: 71%
“…Our patient presented with typical symptoms and signs of subacute prurigo, a prurigo variant that is characterized by severely pruritic and excoriated papules that are smaller and less elevated than those of prurigo nodularis; however, the histopathologic findings, in particular the dense infiltration of neutrophils with scant eosinophils, were atypical for subacute prurigo, which usually shows spongiosis and a mixed perivascular and/or perifollicular infiltrate with scattered interstitial eosinophils 1,2 . Surprisingly, linear BMZ deposits of IgA and C3 were detected by DIF, and a diagnosis of LAD was made.…”
Section: Discussionmentioning
confidence: 71%
“…[30]. Alle Patienten litten seit mehr als 6 Monaten an der Erkrankung (Mittelwert: 1,7 Jahre), und bei den meisten Patienten hatten vorangegangene Therapien, u.a.…”
Section: Materials Und Methode Patientenkollektivunclassified
“…Zu den Therapieverfahren bei Prurigo simplex subacuta zählen, neben der kausalen Therapie bei sekundären Formen, interne, externe und intrafokale Glukokortikoide, Teerpräparate, juckreizstillende topische Substanzen wie Polidocanol, interne Antihistamini-Die Prurigo simplex subacuta ist eine subakut bis chronisch verlaufende Dermatose, welche durch stark juckende urtikarielle Papeln gekennzeichnet ist und häufiger bei Frauen als bei Männern vorkommt [3,8,12,30]. Haupterkrankungsalter ist bei Frauen die 3.…”
Section: Balneophotochemotherapie Der Prurigo Simplex Subacutaunclassified
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“…Ackerman [1] described “a maddeningly pruritic, persistent itchy red bump disease” clinically resembling dermatitis herpetiformis or transient acantholytic ­dermatosis with histological features similar to papular urticaria [1]. Others used the terms subacute prurigo [2], papular eruption in black men [3], papular dermatitis [4, 5], and chronic papular dermatitis in adult men [6]. …”
Section: Introductionmentioning
confidence: 99%