Primary cutaneous aspergillosis in an immunocompetent individual

Ajith, C; Dogra, Sunil; Radotra, BD; Chakrabarti, Arunaloke; Kumar, Bhushan

doi:10.1111/j.1468-3083.2006.01465.x

Cited by 24 publications

(18 citation statements)

References 9 publications

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“…The widespread distribution and morphology of the lesion misled the dermatologist for erythema nodosum leprosum but mycological and histological examination confirmed the diagnosis. Although complete healing of cutaneous aspergillosis after oral antifungals is rare, our patient recovered completely after first line treatment with itraconazole 10 13. Itraconazole was given as 200 mg orally twice daily for 4 weeks.…”

Section: Treatmentmentioning

confidence: 82%

Primary cutaneous aspergillosis due toAspergillus tamariiin an immunocompetent host

Sharma¹,

Yenigalla²,

Naidu³

et al. 2013

BMJ Case Reports

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Primary cutaneous aspergillosis is a rare disease usually caused by Aspergillus fumigatus, Aspergillus flavus, Aspergillus terreus and Aspergillus ustus. It is usually seen in immunocompromised hosts, though some cases are also reported in immunocompetent hosts. We present a case of an immunocompetent farmer who presented with generalised nodules and plaques, mimicking erythema nodosum leprosum but turned out to be cutaneous aspergillosis caused by Aspergillus tamarii. The characteristic ascospores of Aspergillus species were found in skin lesions on fungus isolated in culture. The patient showed excellent response to antifungal therapy.

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Section: Treatmentmentioning

confidence: 82%

Primary cutaneous aspergillosis due toAspergillus tamariiin an immunocompetent host

Sharma¹,

Yenigalla²,

Naidu³

et al. 2013

BMJ Case Reports

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“…Nodules and pustular lesions although rare might also occur. [135] Our patient presented with nodules, which ulcerated after attempted incision and drainage in a referral clinic. There have been cases reported in the axillae and perineum of neonates, and in these patients the lesions typically originate as erythematous patches or Plaque that develop into pustules and eventually ulcerate to form necrotic eschars.…”

Section: Discussionmentioning

confidence: 98%

Primary cutaneous aspergillosis in an immunocompetent patient

Tahir

Garbati

Nggada

et al. 2011

J Surg Tech Case Report

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We present a 32-year-old woman with primary cutaneous aspergillosis and an apparently normal immune status. She is a dietitian who carried out research on Aspergillus contamination of palm oil over a six-month period, during which she apparently shaved her axillae and perineum using a safety razor blade. She presented with nodular lesions, which became extensive ulcers after an attempt at incision and drainage. Diagnosis was based on culture and histology. The patient was treated with itraconazole 200 mg twice a day, with surgical excision and a rhomboid flap cover of the axillae. She has remained disease-free five years after discharge. This highlights the likely benefits of a combination of surgical excision and drug therapy, in achieving a cure in this patient.

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“…Out of 113 manuscripts resulting from the literature search, 78 contained eligible patients, resulting in a total of 130 unique eligible PCA cases. [ 7 – 84 ] The cases were reported from the years 1967 to 2015 (Supplementary Table 1). Most of the manuscripts consisted of single case reports or small case series.…”

Section: Resultsmentioning

confidence: 99%