Primary Colonic Follicular Lymphoma Presenting as Four Diminutive Sessile Polyps Found Incidentally During Colonoscopy

Abstract

Follicular lymphomas, which typically arise in the lymph nodes with spleen, liver, and bone marrow involvement, have generally low occurrence rates in Asian countries as compared with Western countries. Follicular lymphomas of the gastrointestinal tract are rare, and primary colonic follicular lymphomas are particularly rare compared with others found in the small intestine and duodenum. Colonoscopic imaging of colonic lymphomas, including follicular lymphoma, may reveal mucosal ulcerations, erosions, indurations, polypoid mass-like lesions, and diffuse mucosal nodularity. Herein, we report a unique case of a follicular lymphoma of the transverse colon characterized by four sessile diminutive polyps located intermittently with multiple lymph node involvement in a 62-year-old man.

Primary Colorectal Follicular Lymphoma Observed by Magnifying Endoscopy, with a Five-year Follow-up

“…The median age was 65.8 (range: 56-75) years old, and the male-to-female ratio was 4:4. According to the Lugano classification, the ratio of clinical stages I:II1 was 6: 2 and the endoscopic appearances of papular, polypoid and flat elevated type were observed in 4, 2 and 2cases, respectively (7)(8)(9)(10)(11)(12)(13)(14), and all of which showed raised lesions (Table). Nakamura et al reported that the endoscopic features of intestinal lymphoma may be classified as polypoid, ulcerative, multiple lymphomatous polyposis (MLP), diffuse, and mixed type (15).…”