Primary central nervous system lymphoma mimicking cerebellopontine angle tumour

Berrocal-Izquierdo, Nuria; Muñoz, F.; Bosch, Jules M.M. van den; Molet, J.

doi:10.1016/j.nrleng.2016.06.010

Cited by 3 publications

(4 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Primary central nervous system lymphoma (PCNSL) presents as a single lesion in 60% to 70% of patients, and diffuse large B-cell lymphoma accounts for the majority (90%) of cases [5], most commonly located in the hemisphere (38%), thalamic/basal ganglia (16%), corpus callosum (14%), periventricular area (12%), or cerebellum (9%) [6]. Cerebellopontine angle lymphoma is very rare; however, it must be kept in differential diagnosis, as accurate diagnosis is imperative for proper management of the patient.…”

Section: Discussionmentioning

confidence: 99%

Lymphoma of the cerebellopontine angle mimicking metastasis lesion: A case report

Tlemcani¹,

Sahri²,

Hakkou³

et al. 2023

World J. Adv. Res. Rev.

View full text Add to dashboard Cite

Primary lymphoma of the cerebellopontine angle (CPA) is rare and uncommon in the central nervous system, accounting for approximately 0.2-2% of all brain tumors. To our knowledge, there have only been 32 cases reported worldwide so far. Here, we report a rare case of B-cell lymphoma in a 56-year-old woman who presented with seizure, dysphagia, and dizziness and showed a lesion involving the left CPA, right frontal horn and septum pellucidum on magnetic resonance imaging (MRI). The primary diagnosis was metastatic tumor; however, Stereotactic biopsy on left CPA lesion was done, and the histological features confirmed the diagnosis of B-cell malignant lymphoma. The patient was treated with chemotherapy, with complete resolution of symptoms after the first chemotherapy session.

show abstract

Section: Discussionmentioning

confidence: 99%

Lymphoma of the cerebellopontine angle mimicking metastasis lesion: A case report

Tlemcani¹,

Sahri²,

Hakkou³

et al. 2023

World J. Adv. Res. Rev.

View full text Add to dashboard Cite

show abstract

“…However, increasing experience with CT and MRI studies allow greater accuracy in the preoperative differential diagnosis [35]. The common differential diagnosis includes schwannoma (70%-90%), meningioma (5%-10%), epidermoid cyst (5%-7%), metastatic tumors and glomus jugulare tumors [5,6,8,14,35,36]. Kendall et al analyzed 208 cases of CPA tumours and found bony erosion of the internal auditory canal in 98 cases on CT scan, with 93.9% of the of these being acoustic neuromas [37].…”

Section: Discussionmentioning

confidence: 99%

“…Most PCNSLs are supratentorial in a central location, including the corpus callosum, basal ganglia, thalamus, and paraventricular region [3][4][5]. Infratentorial PCNSL is rare, accounting for only 10%-20% of all PCNSLs [6]. PCNSL of the cerebellopontine angle (CPA) is extremely rare and would probably be mistaken for other CPA lesions such as vestibular schwannomas or meningiomas [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

“…Infratentorial PCNSL is rare, accounting for only 10%-20% of all PCNSLs [6]. PCNSL of the cerebellopontine angle (CPA) is extremely rare and would probably be mistaken for other CPA lesions such as vestibular schwannomas or meningiomas [4][5][6]. To the best of our knowledge, only 26 cases of CPA PCNSLs have been previously reported in the English literature .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Primary Central Nervous System Lymphoma of the Cerebellopontine Angle: Epidemiological Characteristics and Imaging Features May Be Helpful for Making an Accurate Preoperative Diagnosis

Zheng

Zhang

Huang

et al. 2021

Preprint

View full text Add to dashboard Cite

Purpose Primary central nervous system lymphoma (PCNSL) of the cerebellopontine angle (CPA) is rare, thus the preoperative diagnosis is still a challenge.MethodsWe searched the database at our institution and performed a search of English literature in PubMed and Google Scholar. Keywords used were as follows: “primary central nervous system lymphoma”; “cerebellopontine angle”; “lymphoma”. Only cases in the English language that were located in the CPA and contained adequate clinical information pertinent to the analysis were included.Results297 cases of pathologically confirmed PCNSLs were recorded between January 2009 and October 2020 at our institution. 6 cases were located in the CPA, accounting for 2.0% of all PCNSLs. 26 cases meeting the above criteria were found in the literature. Including ours, a total of 32 patients were analyzed. Females were more frequently affected (F/M ratio, 2.2:1). There was a preponderance of left-sided lesions in the PCNSLs of the CPA (L/R ratio, 1.5:1). On CT, 80.0% of them presented as hyperdense lesions. On T1-weighted image, 66.7% appeared isointense. While on T2-weighted image (T2WI), 68.4% appeared isointense/hypointense. After contrast administration, 86.2% presented intense homogeneous enhancement.ConclusionPCNSL of the CPA is extremely rare, accounting for 2.0% of all PCNSLs in our study. There is a preponderance of females and left-sided lesions in this disease. Contrast-enhanced magnetic resonance imaging with T2WI is very helpful in the preoperative diagnosis of the CPA PCNSL. Although rare, lymphoma should be included in the differential diagnosis of CPA lesions.

show abstract

A case of primary central nervous system lymphoma with dizziness and hearing impairment as the initial symptoms

2022

View full text Add to dashboard Cite

Primary central nervous system lymphoma (PCNSL) is a lymphoma that is confined to the brain and spinal cord. The clinical manifestations vary depending on the site of origin, but the main presenting complaint in most cases is loss of memory.In this study, we encountered a case of PCNSL in which the patient presented to the ENT department with the complaints of dizziness and hearing impairment, which led to the diagnosis. At the first visit, there were no neurological findings other than dizziness and hearing impairment, but as the disease progressed, many neurological findings became evident. Since the symptoms of PCNSL progress rapidly, it is necessary to perform detailed examinations, such as imaging tests, at an early stage without overlooking the slightest signs.

show abstract

Primary central nervous system lymphoma mimicking cerebellopontine angle tumour

Cited by 3 publications

References 7 publications

Lymphoma of the cerebellopontine angle mimicking metastasis lesion: A case report

Lymphoma of the cerebellopontine angle mimicking metastasis lesion: A case report

Primary Central Nervous System Lymphoma of the Cerebellopontine Angle: Epidemiological Characteristics and Imaging Features May Be Helpful for Making an Accurate Preoperative Diagnosis

A case of primary central nervous system lymphoma with dizziness and hearing impairment as the initial symptoms

Contact Info

Product

Resources

About