Primary bone tumors: value of MR angiography for preoperative planning and monitoring response to chemotherapy.

Abstract

OBJECTIVE. The purposes of our study were to investigate the use of MR angiography with two-(2D) and three-dimensional (3D) displays in evaluating vascular morphohogy of musculoskeletal neoplasms for preoperative planning of limb-salvage surgery and to assess the use of MR angiography for monitoring changes in neovascularity and evaluating response to chemotherapy. SUBJECTS AND METHODS. We

Musculoskeletal Tumors: How to Use Anatomic, Functional, and Metabolic MR Techniques

“…For this purpose, conventional MR sequences are frequently entirely adequate in defining the full extent of a tumor, its relationship to the adjacent neurovascular bundle, and nearby joints (1). However, MR imaging may also be used for the roles of detection, characterization, and assessment of a tumor after treatment (both after neoadjuvant therapy before surgery for the assessment of treatment response and after surgery for assessment of postsurgical residual or recurrent disease) (2)(3)(4)(5)(6). The advent of chemical shift MR imaging (in-phase and opposed-phase imaging), diffusionweighted (DW) imaging, perfusion imaging, and MR spectroscopy has advanced the role of MR for characterizing lesions for malignancy and assessing lesions after treatment.…”

Total body MRI-governed involved compartment irradiation combined with high-dose chemotherapy and stem cell rescue improves long-term survival in Ewing tumor patients with multiple primary bone metastases

“…Short tau (time) inversion recovery imaging allows more precise depiction of tumors than spinecho sequences. [25][26][27][28] Several studies comparing scintigraphy with MRI have demonstrated that MRI is more sensitive and more specific than scintigraphy, [29][30][31][32] but to date there are few reports available assessing the potential of TB-MRI. 33 Eustace et al 34 compared TB-MRI and scintigraphy in detecting skeletal metastases in 49 patients with solid tumors.…”

The role of imaging in the staging and treatment planning of primary malignant bone tumors in children

“…In some centers, MR angiography has replaced conventional angiography in the preoperative evaluation of tumor vascularity because it is noninvasive and provides good visualization of peripheral vascular branches and tumor neovascularity in patients [17].…”