Primary aspergillosis of the spine mimicking Pottʼs paraplegia.

McKee, Delores; Barr, W M; Bryan, Corinna Susanne; Lunceford, E. M.

doi:10.2106/00004623-198466090-00030

Cited by 32 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In adults, vertebrae is also the most common infection site but most of the time due to hematogenous spread or direct inoculation due to trauma with penetrating injury/surgical procedures [2][3][4][5][6][7]. Most cases of Aspergillus osteomyelitis appeared to be affecting immunocompromised hosts with chronic granulomatous infections and immunodeficiency condition [2,[4][5][6][8][9][10]. Among adults, prolonged and high dose immunosuppressive drug therapy is considered the most important predisposing condition [2,4].…”

Section: Discussionmentioning

confidence: 99%

“…Unlike Candida, which is the most common organism causing mycotic infections [16,17], Aspergillus is slow growing, difficult to isolate and most of the time is a contaminant since the spores are really small [9,18]. Therefore, a culture and histopathological examination are still important to obtain the correct diagnosis [7,9,18].Another proposed method for diagnostic are Galactomannan (GM) and (1→3)-β-d-glucan (BG) antigen quantification by enzyme-linked immunosorbent assay and detection of fungal DNA by PCR methods or single nucleotide polymorphism (SNP) markers.This test is not easily available and has not been studied as an indicator for osteomyelitis caused by Aspergillus.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Osteomyelitis of the Hip secondary to Aspergillus fumigatus - A Case Report and Comprehensive Review of the Literature

Sj¹,

Hadi²

2014

Journal of Immunology and Infectious Diseases

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Osteomyelitis of the Hip secondary to Aspergillus fumigatus - A Case Report and Comprehensive Review of the Literature

Sj¹,

Hadi²

2014

Journal of Immunology and Infectious Diseases

View full text Add to dashboard Cite

“…2,14 Biopsy specimens stained with hematoxylin and eosin, periodic acid-Schiff, or methenamine silver reveal acute-angle branching septate hyphae and larger numbers of conidia characteristic of the species. 8,14,15,34,40 Fluorescein labelled antibodies and antigen detection in sera by enzyme-linked immunosorbent assay or radioimmunoassay are not routinely available but may be useful to detect early disease.13,14…”

Section: Diagnosismentioning

confidence: 99%

Aspergillosis of the Cranial Base

Carr¹,

Cusimano²,

Müller³

et al. 1994

Skull Base

View full text Add to dashboard Cite

A 65-year-old male of Italian descent presented with a 1-week history of hoarseness, dysphagia, left otalgia, and decreased hearing. He complained of right frontooccipital headaches of 1 month's duration. He had been well until 4 months prior when he had an abscessed left maxillary molar extracted with a subsequent maxillary sinus infection. He had taken multiple courses of antibiotics and was currently on cephalexin. He reported a 20-lb weight loss over this time, which he associated with reduced ability to eat because of oral pain. His past medical history included vocal cord polypectomy 12 years prior to admission, from which he recovered well, a 20-packa-year smoking habit that he had ended 6 months previously, and daily moderate alcohol intake.On examination he was edentulous, with a fibrous epulis and a lichenoid white lesion on the right buccal mucosa. On the right side he had an absent gag reflex, paralysis of the right vocal cord in a paramedian position with the left cord compensating, sternomastoid muscle wasting, and weaker shoulder shrugging. There was an old perforation in the right tympanic membrane which was retracted, and the right cervical lymph nodes were palpable.Audiometry revealed a sensorineural hearing loss on the right side.Skull radiographs, computed tomography of the head, skeletal survey, cerebral angiograms, and chest radiographs were within normal limits. Gallium bone scan showed increased uptake in the right petrous bone. Repeated lumbar punctures did not reveal organisms.He was admitted to hospital and started on oral dexamethasone. His blood sugar became erratic and was controlled with insulin. He had an episode of aspiration pneumonia treated with penicillin and tobramycin. With worsening clinical status computed tomography of the head was repeated, revealing bony erosion near the right jugular foramen (Fig. 1). Magnetic resonance imaging showed a pancake-shaped lesion close to the right jugular foramen thought to be representative of thickened meninges (Fig. 2).One month after admission he underwent a posterior fossa craniotomy and dural biopsy. Histology revealed fungal hyphae, necrosis, and chronic inflammatory cell infiltrate (Fig. 3). Cultures grew Aspergillus. 159Skull

show abstract

TB Spine in Special Conditions

Mehta¹,

Nico²

2022

Tuberculosis of the Spine

View full text Add to dashboard Cite

Primary aspergillosis of the spine mimicking Pottʼs paraplegia.

Cited by 32 publications

References 8 publications

Osteomyelitis of the Hip secondary to Aspergillus fumigatus - A Case Report and Comprehensive Review of the Literature

Osteomyelitis of the Hip secondary to Aspergillus fumigatus - A Case Report and Comprehensive Review of the Literature

Aspergillosis of the Cranial Base

TB Spine in Special Conditions

Contact Info

Product

Resources

About