Primary Angiosarcoma of Adrenal Gland Presenting as Paraneoplastic Syndrome: Case Report

Bosco, Peter J.; Silverman, Mark L.; Zinman, Leonard

doi:10.1016/s0022-5347(17)38012-6

Cited by 16 publications

(11 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patients present in a variety of ways including flank or abdominal pain, palpable mass, fatigue, weight loss, fever, or clinically asymptomatic with a mass detected on incidental imaging. Table 1 summarizes the age, sex, type of presentation, treatment, and follow-up for previously reported cases 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27. Patients who present with systemic symptoms tend to have worse outcomes than those with localized symptomatology.…”

Section: Discussionmentioning

confidence: 99%

Angiosarcoma of the Adrenal Gland Treated Using a Multimodal Approach

Fuletra

Ristau

Milestone

et al. 2017

Urology Case Reports

View full text Add to dashboard Cite

Angiosarcoma of the adrenal gland is an extremely rare malignancy. We report a case of a 59-year-old female who presented with abdominal pain and profound anemia. A 7 cm enhancing, lipid-poor adrenal mass with calcifications that extended posterior to the vena cava was identified on imaging. Patient underwent right adrenalectomy with retroperitoneal lymph node dissection. Pathology demonstrated angiosarcoma of the adrenal gland. Consolidative treatment included adjuvant radiation and chemotherapy. Patient remains disease free 1.5 years following treatment. Prior reported literature on the diagnosis and management of adrenal angiosarcoma is reviewed.

show abstract

Section: Discussionmentioning

confidence: 99%

Angiosarcoma of the Adrenal Gland Treated Using a Multimodal Approach

Fuletra

Ristau

Milestone

et al. 2017

Urology Case Reports

View full text Add to dashboard Cite

show abstract

“…The disease usually starts with pain and presence of abdominal mass, followed by significant weight loss, fever episodes and weakness. In six cases described in the literature the disease was asymptomatic but in four cases it was associated with paraneoplastic syndrome and distant metastases to bone and liver 38 , 39 ) . One patient had an unusual association with Cushing’s disease while in one patient an adrenal tumor had accidentally been discovered 40 , 41 ) .…”

Section: Discussionmentioning

confidence: 99%

A Vinyl Chloride-exposed Worker with an Adrenal Gland Angiosarcoma: A Case Report

Criscuolo

Valerio

Gianicolo³

et al. 2014

Ind Health

View full text Add to dashboard Cite

Adrenal epithelioidangiosarcoma (AEA) is a rare neoplasm that accounts for less than 1% of sarcomas. Due to its rarity, it can easily be misdiagnosed, both by the clinician and the pathologist. Data on the patient’s occupational history was collected and analyzed. The bibliographic data was found on the PUBMED bibliographic search site after entering the word “extrahepaticangiosarcoma”. We report a case of adrenal epithelioidangiosarcoma (AEA) in a 68 yr-old Caucasian male factory worker exposed to Vinyl Chloride (VC) for 15 yr. He underwent surgery, chemotherapy and radiotherapy. Hepatic angiosarcoma is a known consequence of VC exposure, but occupational causality of extra-hepatic angiosarcoma is controversial. Extra-hepatic angiosarcomas have been reported in VC workers, but never AEA. Cancerogenic effects of VC involve all endothelial areas of the body and extra-hepatic endothelial tumors may also be caused by this substance. This is the first published report of AEA diagnosed in a worker exposed to VC.

show abstract

“…According to Rosen et al (1988), MeisKindblom and Kindblom (1998) and Deyrup et al (2009) (Kareti et al, 1988;Livatidou et al, 1991;Bosco et al, 1991;Wenig et al, 1994;Otal et al, 1999;Ben Izhak et al, 1999;Krüger et al, 2001;Croitoru et al, 2001;Invitti et al, 2001;Pasqual et al, 2002;Lepoutre-Lussey et al, 2012;Derlin et al, 2012).…”

Section: Review Discussion and Conclusionmentioning

confidence: 99%

Adrenal Gland Hemangiosarcoma in a Patient with Chronic Myeloid Leukaemia

Bacalja¹,

Ulamec²,

Rako³

et al. 2013

IJCRM

View full text Add to dashboard Cite

Hemangiosarcomas are rare tumours, predominantly affecting adult and elderly patients. Most frequently they involve the skin, although they can occur in visceral organs and other tissues. Hemangiosarcomas pursue an aggressive clinical course with high mortality rates. Primary adrenal hemangiosarcoma is extremely rare. We report a case of a 64-year-old male patient. He underwent ultrasound and computed tomography scan because of pain in his left lumbar area present over the previous 2 months. Tumor mass of the adrenal gland was found and he underwent left adrenalectomy. Macroscopically, cystic tumor that measured up to 9 cm in diameter was found. Histological diagnosis was hemangiosarcoma. The patient was being treated for chronic myeloid leukaemia for 7 years. During the time the adrenal tumor was diagnosed, he had been in remission. He died one and a half months after tumor resection because of profound bleeding in postoperative area. To our knowledge, this is the first case of a primary adrenal gland hemangiosarcoma in a patient treated for chronic myeloid leukaemia.

show abstract

Primary Angiosarcoma of Adrenal Gland Presenting as Paraneoplastic Syndrome: Case Report

Abstract: Angiosarcoma is an uncommon neoplasm that rarely involves the adrenal gland. We report on a patient with primary angiosarcoma of the adrenal gland who presented with symptoms best characterized as a paraneoplastic syndrome.

Cited by 16 publications

References 7 publications

Angiosarcoma of the Adrenal Gland Treated Using a Multimodal Approach

Angiosarcoma of the Adrenal Gland Treated Using a Multimodal Approach

A Vinyl Chloride-exposed Worker with an Adrenal Gland Angiosarcoma: A Case Report

Adrenal Gland Hemangiosarcoma in a Patient with Chronic Myeloid Leukaemia

Contact Info

Product

Resources

About