Primary anal mucinous adenocarcinoma: A case series

Diffaa, A.; Samlani, Zouhour; Elbahlouli, Abouch; Rabbani, K.; Narjis, Y.; Elamansouri, Fadoua; Ettalbi, Salwa; Boukind, Elhassan; Belabidia, Badia; Idrissi, Hamid El; Krati, K.

doi:10.1016/j.ajg.2010.12.001

Cited by 7 publications

(3 citation statements)

References 12 publications

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“…7 Clinically the patient may manifest pain and rectal bleeding, anal abscess, perianal mass and edema and chronic discharge. 1,2,8,9 Digital rectal examination (DRE) may reveal only a hardened area adjacent to the fistula. 10 Furthermore, the stenosis and anal pain may limit the physical examination, delaying the diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Mucinous adenocarcinoma arising from recurrent perianal fistula in patient with Crohn's disease: case report

Alencar

Corrêa

Bezerra

et al. 2014

Journal of Coloproctology

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Introduction Anal carcinoma is a rare variant of epithelial tumors of the anal canal. When associated with chronic and active anal fistulas, usually this is an aggressive cancer that has difficult diagnosis and poor prognosis. Anal fistulas are a common manifestation of Crohn's disease (CD). This study aims to report a case of mucinous adenocarcinoma originating from recurrent perianal fistula in patients with CD. Case report A man of 43 years, with melanoderma, complaining of perianal tumors, anal pain and mucopurulent secretion, the patient was diagnosed with fistulae. Colonoscopy revealed a chronic inflammatory process associated with villous polypoid lesion in the colonic and rectal mucosa. In a new episode, where it was diagnosed, chronic colitis of rectum and sigmoid was being prescribed sulfasalazine with improvement. There were relapses and the patient underwent repeated fistulectomias. After investigation, CD was diagnosed. Computed tomography (CT) of abdomen and pelvis showed multiple perineal and gluteal collections, and the patient underwent abdominoperineal resection of the rectum. Anatomopathological exam showed invasive mucinous adenocarcinoma. A new CT showed residual growth of the lesion. The patient was referred to the oncology referral service, where chemotherapy and radiotherapy were planned. The patient developed unfavorably, and his death occurred two months after treatment.

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Section: Discussionmentioning

confidence: 99%

Mucinous adenocarcinoma arising from recurrent perianal fistula in patient with Crohn's disease: case report

Alencar

Corrêa

Bezerra

et al. 2014

Journal of Coloproctology

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“…Anal mucinous adenocarcinoma [ Figure 16 ] is a rare malignancy accounting for about 3% of anal cancers. [ 23 24 ] Squamous cell carcinoma is similarly rare, but is strongly associated with the human papillomavirus. Presentation of anal cancer is variable, but generally includes anal pain, bleeding, or itching.…”

Section: Casesmentioning

confidence: 99%

MRI of Uncommon Lesions of the Large Bowel: A Pictorial Essay

Lee

Glockner

2014

Journal of Clinical Imaging Science

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“…Due to their association with a symptomatic perianal fistula, malignant transformation is often initially overlooked. 3,4 We present such a case along with a review of the available literature concerning its aetiopathogenesis.…”

Section: Introductionmentioning

confidence: 99%