Primary Alveolar Soft Part Sarcoma of the Scapula

Sahraoui, Ghada; Boujelbène, Nadia; Doghri, Raoudha; Mrad, Karima

doi:10.4236/ojo.2017.71002

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…Very few cases have been reported in scapular region. Authors found that tumor presented with bony erosion and poorly defined tumor margins [10][11][12][13] and their relevant findings were summarized in Table 1.…”

Section: Discussionmentioning

confidence: 99%

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Alveolar soft part sarcoma–presenting as an unusual scapular swelling- A rare case report

Maurya

Kumar²,

Akhtar³

2022

JDPO

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Alveolar soft part sarcoma (ASPS) is a very rare soft tissue tumor of unknown histogenesis and has propensity for recurrence and distant metastasis. It commonly occurs in the head neck region and on extremities in adolescents and young adults. Less number of cases have been reported in the scapular region so far. Till now, no definite treatment regime is available for ASPS; early diagnosis plays a pivotal role in its management and patient outcome. Here, we are presenting a case of 23 years old male presenting with a recurrent swelling in right scapular region. It was diagnosed as ASPS on the basis of radiology, histomorphology and immunohistochemistry.

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Section: Discussionmentioning

confidence: 99%

“…For ASPS prognostic risk factors are age >10 years, tumor size >5cm and presence of distant metastases. 7,9,12,13 Surgical excision remains the primary modality of treatment for ASPS. In advance disease, it may be followed by adjuvant therapy.…”

Section: Discussionmentioning

confidence: 99%

Alveolar soft part sarcoma–presenting as an unusual scapular swelling- A rare case report

Maurya

Kumar²,

Akhtar³

2022

JDPO

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Molecular Landscape in Alveolar Soft Part Sarcoma: Implications for Molecular Targeted Therapy

Soheilifar

Taheri

Emameh

et al. 2018

Biomedicine & Pharmacotherapy

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Primary Alveolar Soft Part Sarcoma of Bone: A Rare Occurrence in 8 Patients, Posing a Diagnostic Challenge

Kaur

Ramadwar

Gulia

et al. 2022

Archives of Pathology &Amp; Laboratory Medicine

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Context.— Alveolar soft part sarcoma is a rare soft tissue tumor involving mainly deep soft tissue of the lower extremities. Primary bone involvement is extremely rare. Objective.— To discuss histopathologic and immunohistochemical features of alveolar soft part sarcoma along with challenges in diagnosis and management in the context of primary bone origin. Design.— Our study constituted 8 patients. Data were collected from the Tata Memorial Hospital, Mumbai, India, during a 10-year period. Results.— Five patients in our study were female and 3 were male. Their ages ranged from 13 to 56 years. Primary bone involvement was seen in the humerus, tibia, fibula, radius, calcaneus, and rib. Radiologic impression was that of a primary malignant bone tumor in all patients. Conventional histopathologic features were seen in 7 of 8 patients. Positive immunohistochemical expression for TFE3 was demonstrated in 6 patients. All patients had distant metastasis either at presentation or later in the course of the disease. Surgical excision of the primary tumor and adjuvant chemotherapy formed the basis of treatment. Four patients succumbed to disease and 2 were alive with disease. Conclusions.— Rare occurrences of primary bone alveolar soft part sarcoma posed a diagnostic challenge in the form of differential diagnoses of metastatic tumors resembling it either morphologically or immunohistochemically. The combined application of clinical and radiologic features along with characteristic histomorphology and immunohistochemistry helps to arrive at a definite diagnosis of alveolar soft part sarcoma. Aggressive behavior of this tumor and its refractoriness to conventional chemotherapy were evident from our series.

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Primary Alveolar Soft Part Sarcoma of the Scapula

Cited by 3 publications

References 16 publications

Alveolar soft part sarcoma–presenting as an unusual scapular swelling- A rare case report

Alveolar soft part sarcoma–presenting as an unusual scapular swelling- A rare case report

Molecular Landscape in Alveolar Soft Part Sarcoma: Implications for Molecular Targeted Therapy

Primary Alveolar Soft Part Sarcoma of Bone: A Rare Occurrence in 8 Patients, Posing a Diagnostic Challenge

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