2015
DOI: 10.2169/internalmedicine.54.3267
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Primary Aldosteronism Presenting with an Atypical Aldosterone-renin Ratio in the Acute Phase of Cerebral Hemorrhage

Abstract: The aldosterone-renin ratio (ARR) is considered to be the most reliable and sensitive screening parameter for primary aldosteronism (PA). However, little is known regarding how stroke influences the ARR. We herein present a case of a 35-year-old man who was ultimately found to have PA after diagnostic challenges. The patient showed an atypical ARR in the acute phase of cerebral hemorrhage. We therefore conclude that the ARR may be inappropriately decreased immediately after stroke in patients with PA, presumab… Show more

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Cited by 2 publications
(1 citation statement)
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“…[4] Common factors causing negative ARR include potassium status, sodium loading, pregnancy, antihypertensive drugs, some complicating diseases such as OSA and renal insufficiency and some undiscovered causes. [3,[5][6][7][8][9][10][11][12] These negative ARRs may have different causes, but they all generally occur in the context of normal or normal-high renin. As the ARR is strongly influenced by the PRC as the denominator of the ratio such that minor changes in renin may lead to considerable changes in the ARR.…”
Section: Discussionmentioning
confidence: 99%
“…[4] Common factors causing negative ARR include potassium status, sodium loading, pregnancy, antihypertensive drugs, some complicating diseases such as OSA and renal insufficiency and some undiscovered causes. [3,[5][6][7][8][9][10][11][12] These negative ARRs may have different causes, but they all generally occur in the context of normal or normal-high renin. As the ARR is strongly influenced by the PRC as the denominator of the ratio such that minor changes in renin may lead to considerable changes in the ARR.…”
Section: Discussionmentioning
confidence: 99%