Primary aldosteronism and its various clinical scenarios

Martell-Clarós, Nieves; Abad-Cardiel, M.; Álvarez-Álvarez, Beatriz; García-Donaire, José Antonio; Fernández-Pérez, Cristina

doi:10.1097/hjh.0000000000000546

Cited by 7 publications

(7 citation statements)

References 25 publications

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“…AVS continues to be the gold standard in the guidelines [49]. However, the results of selective AVS should always be assessed in the context of sectional imaging diagnosis and clinical symptoms [5,50].…”

Section: Discussionmentioning

confidence: 99%

“…In den Leitlinien ist die NNVBE weiterhin der Goldstandard [49]. Die Ergebnisse einer selektiven NNVBE sollten jedoch immer im Kontext der Schnittbilddiagnostik und dem klinischen Erscheinungsbild beurteilt werden [5,50].…”

Section: Diskussionunclassified

“…in Kombination mit einer Hypokaliämie und metabolischen Alkalose. Seltener wird ein PHA von einer Hypernatriämie und Hypervolämie begleitet [5]. Bei Patienten mit einem systolischen Blutdruck über 160 mmHg, therapierefraktärer Hypertonie, einer Hypertonie bei Inzidentalom oder familiärer Disposition sollte eine klinische Abklärung hinsichtlich eines PHA erfolgen [6].…”

Section: Introductionunclassified

“…PHA is clinically manifested by arterial hypertension, possibly in combination with hypokalemia and metabolic alkalosis. More rarely, PHA is accompanied by hypernatremia and hypervolemia [5]. Patients with systolic blood pressure above 160 mmHg, refractory hypertension, hypertension with incidentaloma or family history of hypertension should be evaluated clinically for PHA [6].…”

Section: Introductionmentioning

confidence: 99%

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Update: Selective adrenal venous sampling (AVS) – Indication, technique, and significance

Loberg

Antoch

Stegbauer

et al. 2020

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Background Primary aldosteronism (PA) is the most common detectable cause of secondary hypertension. The majority of patients have either an adrenal aldosterone-producing adenoma (APA) or bilateral adrenal hyperplasia (BAH) demanding different therapeutic approaches. Screening tests and imaging cannot reliably distinguish between a unilateral or bilateral PA. Methods This review article gives an overview concerning etiology, diagnostics, and therapeutic options of PA, and reviews the indication, the technique, and relevance of selective adrenal venous sampling (AVS) in the context of the current literature and the authors’ experience. Results AVS can verify or exclude a unilaterally dominated secretion with a high success rate. Patients with PA and a unilateral APA can be treated curatively by adrenalectomy. Conclusions AVS is an established diagnostic examination for differentiation of unilateral from bilateral adrenal disease in patients with PA. Key Points: Citation Format

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Section: Discussionmentioning

confidence: 99%

Section: Diskussionunclassified

Section: Introductionunclassified

Section: Introductionmentioning

confidence: 99%

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Update: Selective adrenal venous sampling (AVS) – Indication, technique, and significance

Loberg

Antoch

Stegbauer

et al. 2020

Rofo

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show abstract

“…En experimentos clásicos, la infusión continua de aldosterona induce retención de sodio con un balance de volumen positivo y, por tanto, hipertensión, seguida del llamado "escape de aldosterona", con restablecimiento del equilibrio homeostático a pesar de la infusión de aldosterona en curso debido al aumento reactivo de renina. Es posible que el mecanismo compensatorio o fenómeno de "escape" esté alterado en los pacientes con HTAR (5) o que la HTAR se encuadre en un escenario clínico inicial de hiperaldosteronismo (6).…”

Section: Hipertensión Arterial Resistenteunclassified