Preventive effect of an iron varnish on bovine enamel erosion in vitro

Kato, Melissa Thiemi; Italiani, Flávia de Moraes; Araújo, Juliana Julianelli de; Garcia, Marina Duarte; Sales-Peres, Sílvia Helena de Carvalho; Buzalaf, Marília Afonso Rabelo

doi:10.1016/j.jdent.2008.11.019

Cited by 31 publications

(46 citation statements)

References 23 publications

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“…Although many studies have demonstrated that Fe 2+ has a protective effect against demineralization by acid challenges [Pecharki et al, 2005;Buzalaf et al, 2006;Martinhon et al, 2006;Kato et al, 2007a, b;Sales-Peres et al, 2007;Kato et al, 2009;Alves et al, 2011], it was not able to promote remineralization of artificial caries lesions in vitro [Alves et al, 2011]. To elucidate the mechanism of Fe 2+ action, this study aimed to verify the influence of Fe 2+ on the structure of HA using synthetic HA powder and an in vitro model that simulates dissolution and precipitation.…”

Section: Discussionmentioning

confidence: 97%

“…Alone, or in combination with other ions such as fluoride and copper, iron has a beneficial impact on the decrease of the cariogenic potential of sugar [Oppermann and Rölla, 1980;Rosalen et al, 1996;Miguel et al, 1997a, b]. Many in vitro and in situ studies showed that Fe 2+ reduces enamel demineralization in highly cariogenic and erosive challenges [Pecharki et al, 2005;Buzalaf et al, 2006;Martinhon et al, 2006;Kato et al, 2007a, b;Sales-Peres et al, 2007;Kato et al, 2009;Alves et al, 2011], which proves the effectiveness of Fe an acid-resistant layer (ferric phosphate) [Torell, 1988], thereby decreasing enamel mineral loss. However, Alves et al [2011] demonstrated that ferrous (Fe 2+ ) sulfate was not able to remineralize artificial caries lesions.…”

mentioning

confidence: 99%

“…Therefore, the effect of iron (Fe 2+ ) in the HA structure on the demineralization and remineralization process is not clear. The possibility of adding iron to different products such as sugar [Oppermann and Rölla, 1980;Rosalen et al, 1996;Miguel et al, 1997a;Pecharki et al, 2005], mouthrinse [Sales-Peres et al, 2007], carbonated or uncarbonated beverages [Kato et al, 2007a, b], and varnish [Kato et al, 2009] can increase the availability of iron in body fluids. Therefore, it is important to understand how the presence of iron during the demineralization and remineralization processes affects HA crystallinity.…”

mentioning

confidence: 99%

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Effect of Iron II on Hydroxyapatite Dissolution and Precipitation in vitro

Delbem¹,

Alves²,

Sassaki

et al. 2012

Caries Res

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The aim of this study was to evaluate the effect of iron II on the dissolution and precipitation of synthetic hydroxyapatite (HA). HA powder was suspended in solutions of iron (0.84 µg/ml, Fe0.84; 18.0 µg/ml, Fe18; 70.0 µg/ml, Fe70), fluoride (1,100 µg/ml, F1,100), and deionized water and submitted to pH cycling. After pH cycling, the samples were analyzed by infrared spectroscopy and X-ray diffraction. The concentrations of fluoride, calcium, phosphorus, and iron were also analyzed. The data were submitted to ANOVA, and analyzed by Tukey’s test (p < 0.05). The infrared spectrum showed a reduction in all bands corresponding to phosphates and hydroxyls and an increase in the carbonate band in the groups with iron. The intensity of the phosphate bands increased and that of the hydroxyl bands decreased in the group F1,100. It was observed that there was a higher concentration of Ca in the group F1,100, with no significant difference between the groups Fe18 and Fe70 (p > 0.05). There was an increase in Fe concentration in the HA directly related to the Fe concentration of the treatment solutions. Results show that the presence of Fe causes the precipitation of apatite with high solubility.

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Section: Discussionmentioning

confidence: 97%

mentioning

confidence: 99%

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confidence: 99%

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Effect of Iron II on Hydroxyapatite Dissolution and Precipitation in vitro

Delbem¹,

Alves²,

Sassaki

et al. 2012

Caries Res

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“…The in vitro model employed has been successfully used to evaluate preventive strategies for dental erosion [Kato et al, 2007[Kato et al, , 2009, allowing discrimination between different treatments.…”

Section: Discussionmentioning

confidence: 99%

“…The design employed in the present study has been used in previous reports [Kato et al, 2007[Kato et al, , 2009 and is detailed below.…”

Section: Methodsmentioning

confidence: 99%

Preventive Effect of Commercial Desensitizing Toothpastes on Bovine Enamel Erosion in vitro

Kato¹,

Lancia

Sales-Peres

et al. 2010

Caries Res

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This study evaluated in vitro commercial desensitizing toothpastes with respect to the prevention of erosion and explored the effect of their agents alone or in combination with fluoride. Bovine enamel blocks were randomly allocated to five groups of 20 and exposed to: Sensodyne ProNamel (1,425 ppm F as NaF, 5% KNO₃), Sensodyne Original (no fluoride, 10% SrCl₂), Colgate Sensitive (1,450 ppm F as sodium monofluorophosphate, 5% K citrate), Crest (fluoride-only toothpaste, 1,100 ppm F as NaF) and water (negative control). A second experiment was conducted with experimental dentifrices containing fluoride (NaF, 1,100 ppm F), 10% SrCl₂, 5% KNO₃or 5% K citrate alone or the latter three combined with F. The samples were submitted to four cycles, alternating demineralization (cola, 10 min) and remineralization (artificial saliva, 1 h). Before and between cyclic de- and remineralization, blocks were treated with slurries of the respective toothpastes or water (1 min). Erosive tissue loss was analyzed by profilometry. Data were analyzed by Kruskal-Wallis and Dunn’s tests (p < 0.05). The mean erosion depth (± SE, µm) was significantly less for Colgate Sensitive (0.04 ± 0.00), Sensodyne Original (0.06 ± 0.01) and Crest (0.07 ± 0.01) than for Sensodyne ProNamel (2.36 ± 0.25) or water (2.92 ± 0.24), which did not significantly differ from each other. Both F and the desensitizing agents alone reduced erosion, but no additive effect was found. In addition, the combination of F and KNO₃ did not reduce erosion. These in vitro results suggest that the presence of fluoride or desensitizing substances in toothpastes, alone or in combination, can reduce erosion of enamel, but this is not valid for all the formulations.

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