Prevention of Edema, Flight Microangiopathy and Venous Thrombosis in Long Flights with Elastic Stockings. A Randomized Trial

Belcaro, Gianni; Cesarone, M. R.; Shah, Sandeep S. G.; Nicolaides, Andrew; Geroulakos, George; Ippolito, E.; Winford, Michelle; Lennox, Andrew; Pellegrini, L; Brandolini, R.; Myers, Kenneth A.; Simeone, E.; Bavera, P; Dugall, Mark; Renzo, A. Di; Moia, Marco

doi:10.1177/000331970205300603

Cited by 76 publications

(63 citation statements)

References 21 publications

(12 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Furthermore, we did not ask our athletes about wearing compression stockings [47]. Elastic compression stockings can prevent the development of oedema in long-haul flights [48]. It would be interesting to determine in future field-studies, whether compression stockings have an influence on the development of peripheral oedemas in ultra-marathoners.…”

Section: Discussionmentioning

confidence: 99%

An increased fluid intake leads to feet swelling in 100-km ultra-marathoners - an observational field study

Cejka

Knechtle

Knechtle³

et al. 2012

Journal of the International Society of Sports Nutrition

View full text Add to dashboard Cite

Background: An association between fluid intake and changes in volumes of the upper and lower limb has been described in 100-km ultra-marathoners. The purpose of the present study was (i) to investigate the association between fluid intake and a potential development of peripheral oedemas leading to an increase of the feet volume in 100-km ultra-marathoners and (ii) to evaluate a possible association between the changes in plasma sodium concentration ([Na

show abstract

Section: Discussionmentioning

confidence: 99%

An increased fluid intake leads to feet swelling in 100-km ultra-marathoners - an observational field study

Cejka

Knechtle

Knechtle³

et al. 2012

Journal of the International Society of Sports Nutrition

View full text Add to dashboard Cite

show abstract

“…All but one of these trials was conducted by a single group of investigators. 140,[143][144][145][146][147][148][149][150] Trials enrolled a mix of low-and increased-risk subjects based on risk factors for VTE, and most studies included persons taking fl ights of . 7 h. Asymptomatic DVT detected by screening ultrasound examination was the primary end point.…”

Section: Risk Of Vtementioning

confidence: 99%

Prevention of VTE in Nonsurgical Patients

Falck‐Ytter

Francis

Johanson

et al. 2012

Chest

1,738

485

View full text Add to dashboard Cite

“…All limited investigation to air travel. Eight of the 9 trials18,27–33 came from the same group of investigators. …”

Section: Resultsmentioning

confidence: 99%

“…Nine studies17,20–22,26,27,30–32 reported the following risk factors in 126 VTE patients: age over 40, 45%; female hormone use, 31%; varicose veins, 19%; obesity, 17%; inherited clotting disorder, 6%; and other factors, 7%. None of these studies compared rates of DVT risk factors in VTE subjects with those of non-VTE subjects.…”

Section: Resultsmentioning

confidence: 99%

“…No studies tested warfarin or unfractionated heparin. Graduated compression stockings, ranging from 12 mmHg to 30 mmHg at the ankle, were evaluated in 6 studies, and 4 of these studies reported a statistically significant benefit 18,26,27,31. Of the 1,237 subjects using compression stockings, only 2 DVTs were found (0.2%), compared to 46 in the 1,245 controls (3.7%).…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Air Travel and Venous Thromboembolism: A Systematic Review

et al. 2007

View full text Add to dashboard Cite

CONTEXT: Despite multiple attempts to document and quantify the danger of venous thromboembolism (VTE) following prolonged travel, there is still uncertainty about the magnitude of risk and what can be done to lower it.OBJECTIVES: To review the methodologic strength of the literature, estimate the risk of travel-related VTE, evaluate the efficacy of preventive treatments, and develop evidence-based recommendations for practice.DATA SOURCES: Studies identified from MEDLINE from 1966 through December 2005, supplemented by a review of the Cochrane Central Registry of Controlled Trials, the Database of Abstracts of Reviews of Effects, and relevant bibliographies. STUDY SELECTION:We included all clinical studies that either reported primary data concerning travel as a risk factor for VTE or tested preventive measures for travel-related VTE. DATA EXTRACTION AND ANALYSIS:Two reviewers reviewed each study independently to assess inclusion criteria, classify research design, and rate methodologic features. The effect of methodologic differences, VTE risk, and travel duration on VTE rate was evaluated using a logistic regression model. DATA SYNTHESIS: Twenty-four published reports, totaling 25 studies, met inclusion criteria (6 casecontrol studies, 10 cohort studies, and 9 randomized controlled trials). Method of screening for VTE [screening ultrasound compared to usual clinical care, odds ratio (OR) 390], outcome measure [all VTE compared to pulmonary embolism (PE) only, OR 21], duration of travel (<6 hours compared to 6-8 hours, OR 0.011), and clinical risk ("higher" risk travelers compared to "lower," OR 3.6) were significantly related to VTE rate. Clinical VTE after prolonged travel is rare [27 PE per million flights diagnosed through usual clinical care, 0.05% symptomatic deep venous thrombosis (DVT) diagnosed through screening ultrasounds], but asymptomatic thrombi of uncertain clinical significance are more common. Graduated compression stockings prevented travel-related VTE (P<0.05 in 4 of 6 studies), aspirin did not, and low-molecular-weight heparin (LMWH) showed a trend toward efficacy in one study.CONCLUSIONS: All travelers, regardless of VTE risk, should avoid dehydration and frequently exercise leg muscles. Travelers on a flight of less than 6 hours and those with no known risk factors for VTE, regardless of the duration of the flight, do not need DVT prophylaxis. Travelers with 1 or more risk factors for VTE should consider graduated compression stockings and/or LMWH for flights longer than 6 hours.

show abstract

Prevention of Edema, Flight Microangiopathy and Venous Thrombosis in Long Flights with Elastic Stockings. A Randomized Trial

Abstract: Considering these observations, Flight Socks are effective in controlling edema and in reducing the incidence of DVT in low-medium-risk subjects, in long-haul flights (7-11 hours).

Cited by 76 publications

References 21 publications

An increased fluid intake leads to feet swelling in 100-km ultra-marathoners - an observational field study

An increased fluid intake leads to feet swelling in 100-km ultra-marathoners - an observational field study

Prevention of VTE in Nonsurgical Patients

Air Travel and Venous Thromboembolism: A Systematic Review

Contact Info

Product

Resources

About